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Factors that influence the sustainability of structured allied health journal...
Abstract Background Structured journal clubs are a widely used tool to promote evidence-based practice in health professionals, however some journal clubs (JC) are more... -
Identifying clinical subgroups in IgG4-related disease patients using cluster...
Abstract Background To explore the clinical patterns of patients with IgG4-related disease (IgG4-RD) based on laboratory tests and the number of organs involved. Methods... -
Risk factors for tuberculosis smear non-conversion in Eden district, Western ...
Abstract Background Tuberculosis (TB) continues to be a major global health problem. While progress has been made to improve TB cure rates, South Africa’s 76 % smear-positive... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Patient’s perception of kidney stone prevention within the emergency departme...
Abstract Background No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives Assess patient... -
What happened and why? A programme theory-based qualitative evaluation of a h...
Abstract Background There is increasing interest in and demands for partnerships between academia and healthcare practices. Few empirical studies have described the influence of... -
User survey finds rapid evidence reviews increased uptake of evidence by Vete...
Abstract Background To provide evidence synthesis for faster-paced healthcare decision-making, rapid reviews have emerged as a streamlined alternative to standard systematic... -
Association between antibiotic consumption and the rate of carbapenem-resista...
Abstract Background This study aimed to investigate the relationship between the rate of carbapenem-resistant Gram-negative bacteria and antibiotic consumption intensity in 153... -
The diagnostic accuracy of the hand-held Raman spectrometer for the identific...
Abstract Background There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to... -
Predicting potential adverse events using safety data from marketed drugs
Abstract Background While clinical trials are considered the gold standard for detecting adverse events, often these trials are not sufficiently powered to detect difficult to... -
Serum amyloid A primes microglia for ATP-dependent interleukin-1β release
Abstract Background Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A... -
Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors ...
Abstract Background Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate... -
Outcomes in randomised controlled trials in prevention and management of cari...
Abstract Background Inconsistent outcome reporting is one significant hurdle to combining results from trials into systematic reviews. Core outcome sets (COS) can reduce this... -
National survey and point prevalence study of sedation practice in UK critica...
Abstract Background The present study was designed to (1) establish current sedation practice in UK critical care to inform evidence synthesis and potential future primary... -
Inter-agency collaboration factors affecting multidisciplinary workers’ abili...
Abstract Objectives This study aimed to clarify the factors of successful inter-agency collaboration that affect multidisciplinary workers’ abilities to identify child... -
Development of a prediction model for bacteremia in hospitalized adults with ...
Abstract Background Cellulitis is a common infectious disease. Although blood culture is frequently used in the diagnosis and subsequent treatment of cellulitis, it is a... -
Prevalence and correlates of substance use among health care students in Nepa...
Abstract Background Substance use among health care students threatens professional standards and the delivery of quality services, potentially placing the public at risk.... -
Consumers attitudes and beliefs towards the receipt of antenatal corticostero...
Abstract Background Active participation of consumers in health care decision making, policy and clinical research is increasingly encouraged by governments, influential bodies... -
Downstream consequences of diagnostic error in pediatric anaphylaxis
Abstract Background Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection...
