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A Formal Total Synthesis of (+)-Zincophorin. Observation of an Unusual Urea-D...
A formal total synthesis of (+)-zincophorin via interception of Miyashita's advanced intermediates is described here. This effort features the first synthetic application of an... -
Generation of <i>Capn9<sup>−/−</sup></i> mice.
(A) Schematic representation of the targeting vector and WT and knock-out (KO) alleles of mouse Capn9. Exons 2 to 9 are indicated by black boxes with exon numbers. The probes... -
Dinuclear Catecholate Helicates: Their Inversion Mechanism
Dinuclear Catecholate Helicates: Their Inversion Mechanism -
r37980778c78--bc1a7e8debaa1c4e7a35f080b451a419
Macrocyclic and fused bicyclic dipeptides are complementary motifs for mimicry of different types of β-turn geometry. Macrocyclic dipeptide mimics have served as precursors for... -
Steering S−H and N−H Bond Activation by a Stable N-Heterocyclic Silylene: Dif...
The strikingly different behavior of the ylide-like, N-heterocyclic silylene LSi: (5: L = CH[(CCH2)CMe(NAr)2]; Ar = 2,6-iPrC6H3) versus its LSi→Ni(CO)3 complex 13 to activate... -
Carrier Multiplication in Graphene
Graphene as a zero-bandgap semiconductor is an ideal model structure to study the carrier relaxation channels, which are inefficient in conventional semiconductors. In... -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
Magnetism of Conjugated Organic Nitroxides: Structural Scaffolding and Excha...
Magnetism of Conjugated Organic Nitroxides: Structural Scaffolding and Exchange Pathways -
Luminescent Lanthanide Oxalatophosphites with a 3D Framework Structure: [Ln(H...
Luminescent Lanthanide Oxalatophosphites with a 3D Framework Structure: [Ln(H2O)(C2O4)0.5(HPO3)]·H2O (Ln = Pr, Nd, and Sm−Lu) -
BaHg<sub>2</sub>Tl<sub>2</sub>. An Unusual Polar Intermetallic Phase with Str...
High yields of the novel BaHg2Tl2 are achieved from reactions of the appropriate cast alloys at ∼400 °C. (Isotypic SrHg2Tl2 also exists.) The tetragonal barium structure... -
r37980778c78--57a8cea71350d32cfb4000e3fbaed833
An efficient and highly stereocontrolled preparation, on a large scale, of two new Wieland−Miescher-type diketones is described. The approach centers on a diastereoselective... -
First Structure of a Cyclopentadienyl Trihydride d<sup>2</sup> System: A Pse...
First Structure of a Cyclopentadienyl Trihydride d2 System: A Pseudotrigonal Prism Rather Than the Expected Pseudooctahedron and Its Mechanism of Hydrogen Scrambling -
r37980778c78--0a7c8c4e29efb10cfac5fdfe3c5dffb5
High yields of the novel BaHg2Tl2 are achieved from reactions of the appropriate cast alloys at ∼400 °C. (Isotypic SrHg2Tl2 also exists.) The tetragonal barium structure... -
Brownian Motion of Graphene
Brownian motion is a manifestation of the fluctuation−dissipation theorem of statistical mechanics. It regulates systems in physics, biology, chemistry, and finance. We use... -
Calpains 8 and 9 showed the same tissue distribution and localization in the ...
(A) Schematic illustrations of mammalian calpains 1, 2, 8, and 9. Calpains 8 and 9 have a typical domain structure like calpains 1 and 2: a regulatory N-terminal pro-domain... -
Alkaline-Earth Metal Mercury Intermetallics <i>A</i><sub>11−<i>x</i></sub>Hg<...
Re-examination of the mercury-rich regions of the Ca−Hg and Sr−Hg phase diagrams has shown that the phases previously identified as “AHg3.6” should be reformulated as... -
<i>Capn8</i> or <i>Capn9</i> deficiency increased the susceptibility to ethan...
(A,B) The gastric mucosa of Capn8−/−, Capn9−/−, and WT mice was sectioned and analyzed by hematoxylin-eosin (H-E) staining (A), and periodic acid-Schiff (PAS) staining (B).... -
Novel 1,4-Homofragmentation via an α-Lactone
Conversion of an α,α-dichloroester to the corresponding α-keto acid was unexpectedly complicated by a novel 1,4-homofragmentation. Investigation of the kinetics of this reaction... -
A Formal Total Synthesis of (+)-Zincophorin. Observation of an Unusual Urea-D...
A formal total synthesis of (+)-zincophorin via interception of Miyashita's advanced intermediates is described here. This effort features the first synthetic application of an...
