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AKT1 restricts the invasive capacity of head and neck carcinoma cells harbori...
Abstract Background In mammals, the AKT/PKB protein kinase family comprises three members (AKT1–3). PI3-Kinase (PI3K), a key oncogene involved in a wide variety of cancers,... -
r37980778c78--473391c4450bbde968c7f9ca4f229501
African-American men with prostate cancer typically develop more aggressive tumors than men from other racial/ethnic groups, resulting in a disproportionately high mortality... -
Mammalian Eps15 homology domain 1 potentiates angiogenesis of non-small cell ...
Abstract Background Non-small cell lung cancer (NSCLC) is a devastating disease with a heterogeneous prognosis, and the molecular mechanisms underlying tumor progression remain... -
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress ...
Abstract Background Ischemia–reperfusion (I/R)-induced acute kidney injury (AKI) not only prolongs the length of hospital stay, but also seriously affects the patient’s survival... -
r37980778c78--ee511ebbaf82c7e0a3e9f953836b20ef
Mitochondrial DNA (mtDNA) mutations cause severe maternally inherited syndromes and the accumulation of somatic mtDNA mutations is implicated in aging and common diseases.... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Regulatory role of heme oxygenase-1 in silica-induced lung injury
Abstract Background Silicosis, a progressive inflammatory lung disease attributed mainly to occupational exposure to silica dust, shows loss of lung function even after... -
r37980778c78--fad9e0f22cc3cfba7524dd133961f2c6
Squamous cell carcinoma–related oncogene (SCCRO, also known as DCUN1D1) is a component of the E3 for neddylation. As such, DCUN1D1 regulates the neddylation of cullin family... -
Activity-based protein profiling guided identification of urine proteinase 3 ...
Abstract Background The pathophysiology of subclinical versus clinical rejection remains incompletely understood given their equivalent histological severity but discordant... -
Transition from Superlithiophobicity to Superlithiophilicity of Garnet Solid-...
All-solid-state Li-batteries using solid-state electrolytes (SSEs) offer enhanced safety over conventional Li-ion batteries with organic liquid electrolytes due to the... -
Additional file 1: of Supervillin promotes epithelial-mesenchymal transition ...
Table S1. Stealth siRNA used in the study. Figure S1. siRNA that targeted supervillin splice isoforms (SV1, SV4, and SV5) reduced the level of each isoform in HCC cells, and the... -
r37980778c78--63d348228602793543956144b74b0720
In this novel motif, scandium atoms define infinite parallel chains of alternate trans-face-sharing cubes and pairs of square antiprisms in which each polyhedron is also... -
r37980778c78--830122c3aec6a08c49ebe526f467e718
Asthma and chronic obstructive pulmonary disease (COPD) exacerbations are commonly associated with respiratory syncytial virus (RSV), rhinovirus (RV) and influenza A virus (IAV)... -
Rac2 is required for alternative macrophage activation and bleomycin induced ...
Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by cellular phenotype alterations and deposition of extracellular matrix proteins. The alternative... -
Proteomic characterization of bovine granulosa cells in dominant and subordin...
Abstract Background Characterization of molecular factors regulating ovarian follicular development is critical to understanding its functional mechanism of controlling the...
