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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--48e514b0289b59e84c3e4ba25ae2ed55
We explored the impact a new quantitative biology course for biology majors had on their ability and confidence to utilize hypothesis testing. Students currently in the... -
Risk factors for poor asthma control and impaired quality of life in a Caribb...
Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial portion of... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
PSA testing patterns in a large Swedish cohort before the implementation of o...
Organized PSA testing for asymptomatic men aged 50–74 years will be implemented in Sweden to reduce opportunistic testing in groups who will not benefit. The aim of this study... -
SUMO conjugation regulates immune signalling
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
The comparison between pulmonary rehabilitation with music therapy and pulmon...
Much emphasis is being placed on the role of music therapy as an easy-to-use, noninvasive and relatively cheap method of asthma treatment. The objective of this interventional... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
dedup_wf_001--76d6c0849b62c1fb0e912d7290bfa4ad
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
dedup_wf_001--5101a4e2d80df72a31b34d26c9459e57
A coke produced using a custom-built sole-heated oven and a coke prepared in a pilot-scale oven from a matched coal, were compared using a range of analytical techniques. The... -
Stakeholder perceptions of public good provision from agriculture and implica...
Agriculture provides many public goods; however the costs and benefits of these are rarely well distributed. Maintaining public good provision often relies on external... -
Ceric ammonium nitrate/acetic anhydride: A tunable system for the O-acetylati...
Esterification of a wide range of partially protected carbohydrate derivatives was achieved using acetic anhydride and a catalytic amount of ceric ammonium nitrate (CAN).... -
Effect of recombinant human granulocyte colony-stimulating factor on lymphocy...
Effect of recombinant human granulocyte colony-stimulating factor on lymphocyte subsets in patients with COVID-19 -
dedup_wf_001--53585fd2ae74e46f2b28de670d1bd787
This paper provides insights into trademark activity at the regional level via two objectives. First, it examines the relationship between technological capabilities and new... -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
dedup_wf_001--521933883ca7afca69dd560601a8468b
The comorbidity between gambling disorder (GD) and buying-shopping disorder (BSD) has led to explore the core features that could be interacting between them. The main aim of... -
Detecting asthma exacerbations using daily home monitoring and machine learning
Objective: Acute exacerbations contribute significantly to the morbidity of asthma. Recent studies have shown that early detection and treatment of asthma exacerbations leads to... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting...
