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Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
dedup_wf_001--48e514b0289b59e84c3e4ba25ae2ed55
We explored the impact a new quantitative biology course for biology majors had on their ability and confidence to utilize hypothesis testing. Students currently in the... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
SUMO conjugation regulates immune signalling
Post-translational modifications (PTMs) are critical drivers and attenuators for proteins that regulate immune signalling cascades in host defence. In this review, we explore... -
Measuring subnational democracy: toward improved regime typologies and theori...
ABSTRACTSocial scientists have been limited in their work by the paucity of global time series data about subnational institutions and practices. Such data could help scholars... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
dedup_wf_001--76d6c0849b62c1fb0e912d7290bfa4ad
Latinos are heavily affected with childhood asthma. Little is known about epigenetic mechanisms of asthma in Latino youth. We conducted a meta-analysis of two epigenome-wide... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
Ceric ammonium nitrate/acetic anhydride: A tunable system for the O-acetylati...
Esterification of a wide range of partially protected carbohydrate derivatives was achieved using acetic anhydride and a catalytic amount of ceric ammonium nitrate (CAN).... -
Effect of recombinant human granulocyte colony-stimulating factor on lymphocy...
Effect of recombinant human granulocyte colony-stimulating factor on lymphocyte subsets in patients with COVID-19 -
Methylation Status of VDR Gene and its Association with Vitamin D Status and ...
Deficiency in circulatory vitamin D level and vitamin D receptor DNA methylation could be associated with weakened innate immune response and increased susceptibility to... -
Depressive symptoms are not associated with long-term integrated testosterone...
The association between depressive symptomatology and endogenous testosterone levels is inconclusive. Large inter- and intra-individual testosterone differences suggest point... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting... -
dedup_wf_001--59716430bf39cad654eeab4b69760468
A physiologically based pharmacokinetic (PBPK) model for di-isononyl phthalate (DiNP) was developed by adapting the existing models for di(2-ethylhexyl) phthalate (DEHP) and... -
Responses of the Mitochondrial Respiratory System to Low Temperature in Plants
ABSTRACTLow-temperature (LT) stress induces significant changes to plant cells including perturbations of various physio-biochemical and metabolic processes, which impact... -
Simultaneous Covariance Inference for Multimodal Integrative Analysis
Multimodal integrative analysis fuses different types of data collected on the same set of experimental subjects. It is becoming a norm in many branches of scientific research,... -
Casein kinases as potential therapeutic targets
Introduction: The conventional term ‘casein kinase’ (CK) denotes three classes of kinases – CK1, CK2 and Golgi-CK (G-CK)/Fam20C (family with sequence similarity 20, member C) –... -
Repeatability study of replicate crash tests: A signal analysis approach
Objective: To provide an objective basis on which to evaluate the repeatability of vehicle crash test methods, a recently developed signal analysis method was used to evaluate... -
Quality of oral anticoagulation control in Chinese patients with non-valvular...
The sex, age, medical history, treatment, tobacco use, race risk (SAMe-TT2R2) Score; the sex, age, medical history, treatment, tobacco use, genotype combination (SAMe-TT2G2)... -
Fractional Exhaled Nitric Oxide as an Inflammatory Biomarker in Chronic Obstr...
We studied whether fractional exhaled nitric oxide (F ENO) can differentiate chronic obstructive pulmonary disease (COPD) with concurrent diagnosis of asthma from COPD-only as...
