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Comparing Models for Early Warning Systems of Neglected Tropical Diseases
Background Early warning systems (EWS) are management tools to predict the occurrence of epidemics of infectious diseases. While climate-based EWS have been developed for... -
Utility of repeated praziquantel dosing in the treatment of schistosomiasis i...
Background Controversy persists about the optimal approach to drug-based control of schistosomiasis in high-risk communities. In a systematic review of published studies, we... -
Co-authorship network analysis: a powerful tool for strategic planning of res...
Background New approaches and tools were needed to support the strategic planning, implementation and management of a Program launched by the Brazilian Government to fund... -
A typology of community and stakeholder engagement based on documented exampl...
Background Despite broad consensus on the importance of community and stakeholder engagement (CSE) for guiding the development, regulation, field testing, and deployment of... -
Impact of Health Research Capacity Strengthening in Low- and Middle-Income Co...
Background Measuring the impact of capacity strengthening support is a priority for the international development community. Several frameworks exist for monitoring and... -
Wolbachia enhances West Nile virus (WNV) infection in the mosquito Culex tars...
Novel strategies are required to control mosquitoes and the pathogens they transmit. One attractive approach involves maternally inherited endosymbiotic Wolbachia bacteria.... -
Bayesian Geostatistical Modeling of Leishmaniasis Incidence in Brazil
Background Leishmaniasis is endemic in 98 countries with an estimated 350 million people at risk and approximately 2 million cases annually. Brazil is one of the most severely... -
Maternal serologic screening to prevent congenital toxoplasmosis: a decision-...
Objective To determine a cost-minimizing option for congenital toxoplasmosis in the United States. Methodology/Principal Findings A decision-analytic and cost-minimization model... -
Impact of increased economic burden due to human echinococcosis in an underde...
Background Ningxia is located in western People's Republic of China, which is hyperendemic for human cystic echinococcosis (CE) throughout the entire area with alveolar... -
Research Capacity Strengthening in Low and Middle Income Countries – An Evalu...
Between August 2012 and April 2013 the Career Development Fellowship programme of the Special Programme for Research and Training in Tropical Diseases (World Health... -
Feasibility of utilizing the SD BIOLINE Onchocerciasis IgG4 rapid test in onc...
As effective onchocerciasis control efforts in Africa transition to elimination efforts, different diagnostic tools are required to support country programs. Senegal, with its... -
Current Pipelines for Neglected Diseases
This paper scrutinises pipelines for Neglected Diseases (NDs), through freely accessible and at-least-weekly updated trials databases. It updates to 2012 data provided by recent... -
Comparison of multi-parallel qPCR and double-slide Kato-Katz for detection of...
There is growing interest in local elimination of soil-transmitted helminth (STH) infection in endemic settings. In such settings, highly sensitive diagnostics are needed to... -
Spatio-temporal distribution of dengue and lymphatic filariasis vectors along...
Background Rapidly increasing temperatures in the mountain region of Nepal and recent reports of dengue fever and lymphatic filariasis cases from mountainous areas of central... -
Methodology for Definition of Yellow Fever Priority Areas, Based on Environme...
Yellow fever (YF) is endemic in much of Brazil, where cases of the disease are reported every year. Since 2008, outbreaks of the disease have occurred in regions of the country... -
Interpreting ambiguous ‘trace’ results in Schistosoma mansoni CCA Tests: Esti...
Background The development of new diagnostics is an important tool in the fight against disease. Latent Class Analysis (LCA) is used to estimate the sensitivity and specificity... -
Moving from rabies research to rabies control: lessons from India
Background Despite the availability of effective interventions and public recognition of the severity of the problem, rabies continues to suffer neglect by programme planners in... -
A Systematic Approach to Capacity Strengthening of Laboratory Systems for Con...
Background The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). To counter... -
Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Cla...
Sole reliance on one drug, Praziquantel, for treatment and control of schistosomiasis raises concerns about development of widespread resistance, prompting renewed interest in... -
Economic Impact of Dengue Illness and the Cost-Effectiveness of Future Vaccin...
Background Dengue illness causes 50–100 million infections worldwide and threatens 2.5 billion people in the tropical and subtropical regions. Little is known about the disease...
