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Utility of repeated praziquantel dosing in the treatment of schistosomiasis i...
Background Controversy persists about the optimal approach to drug-based control of schistosomiasis in high-risk communities. In a systematic review of published studies, we... -
Impact of Health Research Capacity Strengthening in Low- and Middle-Income Co...
Background Measuring the impact of capacity strengthening support is a priority for the international development community. Several frameworks exist for monitoring and... -
Bayesian Geostatistical Modeling of Leishmaniasis Incidence in Brazil
Background Leishmaniasis is endemic in 98 countries with an estimated 350 million people at risk and approximately 2 million cases annually. Brazil is one of the most severely... -
Maternal serologic screening to prevent congenital toxoplasmosis: a decision-...
Objective To determine a cost-minimizing option for congenital toxoplasmosis in the United States. Methodology/Principal Findings A decision-analytic and cost-minimization model... -
Methodology for Definition of Yellow Fever Priority Areas, Based on Environme...
Yellow fever (YF) is endemic in much of Brazil, where cases of the disease are reported every year. Since 2008, outbreaks of the disease have occurred in regions of the country... -
Moving from rabies research to rabies control: lessons from India
Background Despite the availability of effective interventions and public recognition of the severity of the problem, rabies continues to suffer neglect by programme planners in... -
A Systematic Approach to Capacity Strengthening of Laboratory Systems for Con...
Background The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). To counter... -
Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Cla...
Sole reliance on one drug, Praziquantel, for treatment and control of schistosomiasis raises concerns about development of widespread resistance, prompting renewed interest in... -
Economic Impact of Dengue Illness and the Cost-Effectiveness of Future Vaccin...
Background Dengue illness causes 50–100 million infections worldwide and threatens 2.5 billion people in the tropical and subtropical regions. Little is known about the disease... -
Projecting the long-term impact of school- or community-based mass-treatment ...
Background Schistosomiasis remains a significant health burden in many areas of the world. Morbidity control, focused on limiting infection intensity through periodic delivery... -
Research on Motor Neuron Diseases Konzo and Neurolathyrism: Trends from 1990 ...
Konzo (caused by consumption of improperly processed cassava, Manihot esculenta) and neurolathyrism (caused by prolonged overconsumption of grass pea, Lathyrus sativus) are two... -
Diagnosis of Visceral Leishmaniasis in Bihar India: Comparison of the rK39 Ra...
Background Antibody-detecting rapid diagnostic tests (RDTs) against rK39 are available to aid in the diagnosis of visceral leishmaniasis (VL). Although these rK39 RDTs have been... -
Tools to Support Policy Decisions Related to Treatment Strategies and Surveil...
Background Appropriate diagnostics to monitor disease trends and assess the effectiveness and impact of interventions are essential for guiding treatment strategies at different... -
Neuropathic pain and psychological morbidity in patients with treated leprosy...
Background Neuropathic pain has been little studied in leprosy. We assessed the prevalence and clinical characteristics of neuropathic pain and the validity of the Douleur... -
Deaths from Symptomatically Identifiable Furious Rabies in India: A Nationall...
Background It is estimated that India has more deaths from rabies than any other country. However, existing estimates are indirect and rely on non-representative studies....
