-
Utility of repeated praziquantel dosing in the treatment of schistosomiasis i...
Background Controversy persists about the optimal approach to drug-based control of schistosomiasis in high-risk communities. In a systematic review of published studies, we... -
Impact of Health Research Capacity Strengthening in Low- and Middle-Income Co...
Background Measuring the impact of capacity strengthening support is a priority for the international development community. Several frameworks exist for monitoring and... -
Economical value of vaccines for the developing countries--the case of Instit...
these institutions maintained scientific research programs but had limited capability for meeting good manufacturing practices (GMPs) in vaccine production. The implementation... -
Bayesian Geostatistical Modeling of Leishmaniasis Incidence in Brazil
Background Leishmaniasis is endemic in 98 countries with an estimated 350 million people at risk and approximately 2 million cases annually. Brazil is one of the most severely... -
Maternal serologic screening to prevent congenital toxoplasmosis: a decision-...
Objective To determine a cost-minimizing option for congenital toxoplasmosis in the United States. Methodology/Principal Findings A decision-analytic and cost-minimization model... -
A Research Agenda for Helminth Diseases of Humans: Health Research and Capaci...
Capacity building in health research generally, and helminthiasis research particularly, is pivotal to the implementation of the research and development agenda for the control... -
Epidemiologic Models, Key Logs, and Realizing the Promise of WHA 54.19
During the late 1800s, when trees were cut by handsaw and the logs floated down river by the hundreds to be milled, they occasionally jammed. Skilled lumberjacks could often... -
Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas
Neglected tropical diseases (NTDs) have been recently identified as significant public health problems in Texas and elsewhere in the American South. A one-day forum on the... -
A New European Neglected Diseases Center for Greece?
Following the recently evolving downturn in the Greek economy, there is an opportunity to build a new Hellenic scientific institution for neglected infections of poverty located... -
Methodology for Definition of Yellow Fever Priority Areas, Based on Environme...
Yellow fever (YF) is endemic in much of Brazil, where cases of the disease are reported every year. Since 2008, outbreaks of the disease have occurred in regions of the country... -
Addressing Ethical, Social, and Cultural Issues in Global Health Research
Summary The purpose of this paper is to encourage reflection among the global health research community and the research ethics community about how a wide range of ethical,... -
Moving from rabies research to rabies control: lessons from India
Background Despite the availability of effective interventions and public recognition of the severity of the problem, rabies continues to suffer neglect by programme planners in... -
Meeting cholera's challenge to Haiti and the world: a joint statement on chol...
Cholera in Haiti: Acute-on-Chronic Long before the devastating earthquake on January 12, 2010, Haiti struggled beneath the burdens of intractable poverty and ill health. The... -
A Systematic Approach to Capacity Strengthening of Laboratory Systems for Con...
Background The lack of capacity in laboratory systems is a major barrier to achieving the aims of the London Declaration (2012) on neglected tropical diseases (NTDs). To counter... -
Break Out: Urogenital Schistosomiasis and Schistosoma haematobium Infection i...
Paul J. Brindley, PhD, is a Deputy Editor of PLOS Neglected Tropical Diseases. He is a professor in the Department of Microbiology, Immunology and Tropical Medicine, School of... -
New antipoverty drugs, vaccines, and diagnostics: a research agenda for the U...
On May 5, 2009, the Obama Administration announced its intention to launch an ambitious United States governmental strategy for global health [1–3]. The US Global Health... -
Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Cla...
Sole reliance on one drug, Praziquantel, for treatment and control of schistosomiasis raises concerns about development of widespread resistance, prompting renewed interest in... -
Economic Impact of Dengue Illness and the Cost-Effectiveness of Future Vaccin...
Background Dengue illness causes 50–100 million infections worldwide and threatens 2.5 billion people in the tropical and subtropical regions. Little is known about the disease... -
One More Death from Visceral Leishmaniasis Has Gone by Unnoticed. What Can Be...
In January 2010, a 35-year-old mother from the village Baniyapur in Bihar, the poorest and second most populous state in India, had been weak and very ill for months with high... -
A Research Agenda for Helminth Diseases of Humans: Towards Control and Elimin...
Human helminthiases are of considerable public health importance in sub-Saharan Africa, Asia, and Latin America. The acknowledgement of the disease burden due to helminth...
