159 items found

Types: publication Groups: figshare Tags: 39999 Chemical Sciences not elsewhere classified 69999 Biological Sciences not elsewhere classified Biotechnology Cancer Pharmacology

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  • publication

    5-HT1A receptor ligands and their therapeutic applications: review of new pat...

    Introduction: 5-HT1AR was one of the first discovered serotonin receptors and is one of the most thoroughly studied. Dysfunctions associated with 5-HT1AR neurotransmission are...
  • publication

    Additional file 1: Tables S1-S3. of Endocrine and exocrine pancreatic insuffi...

    Comparision on the disease severity, complication and pancreatic necrosis between NGT, IGT and DM groups. The APACHE II score and Balthazar score in group DM was significant...
  • publication

    Additional file 1 of Anti-malarial activity of traditional Kampo medicine Cop...

    Additional file 1: Table S1. List of crud drug extracts in Kampo library. Table S2. List of compounds in Kampo library. Table S3. In vitro anti-malarial activities against P....
  • publication

    MOESM1 of Availability, accessibility and delivery to patients of the 28 orph...

    Additional file 1: Table S1. Questionnaire addressed to MetabERN centres. Table S2. Responding centres. Table S3. List of the 28 EMA-approved OMPs for HMDs. Table S4. List of...
  • publication

    Kinetics and mechanism of interaction of Pt(II) complex with bio-active ligan...

    Kinetics of interaction between Pt(pic)(H2O)22, 2 (where pic = 2-aminomethylpyridine) with the selected ligands DL-methionine (DL-meth) and DL-penicillamine (DL-pen) have been...
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    Additional file 1 of The use of olanzapine as an antiemetic in palliative med...

    Additional file 1: Supplementary Table 1. Search algorythms used for each database.
  • publication

    Cytotoxic flavonoids from the fruits of <i>Derris indica</i>

    Chemical investigation of the ethyl acetate extract from the fruits of Derris indica has led to the isolation of a new furanoflavonoid derivative, 4′-hydroxypinnatin (1), and...
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    Additional file 2: Table 2. of Risks of hospitalization and drug consumption ...

    Risks of first drug prescription according to first level of Anatomical Therapeutic Chemical (ATC) Classification five or more years from date of diagnosis in CD subjects...
  • publication

    Additional file 1 of Preparation, characterization and in vitro–in vivo evalu...

    Additional file 1: Fig. S1. The survival rate of L02 cells treated by BTZ-NP. Fig. S2. The survival rate of 4T1 cells exposed to blank supermolecular nanovehicles without BTZ....
  • publication

    dedup_wf_001--8bd248a675ad19cefafb67a3895f7224

    Additional file 1: Supplementary Table 1. List of Primary Antibodies and Conditions of Use. Supplementary Table 2. Composition of Zyflamend [82].
  • publication

    Hepatoprotective effect of chiisanoside against acetaminophen-induced acute l...

    This study was designed to investigate the hepatoprotective effect of chiisanoside (CSS) and its possible mechanisms on acetaminophen (APAP)-induced acute liver damage in mice....
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    dedup_wf_001--9ca35d899b36adee8f0ffff74c62d80a

    Background: Studies evaluating the impact of age and potentially inappropriate medication (PIM) on avoidable adverse drug reactions (ADRs) are scarce. Methods: In this...
  • publication

    Listening to music with personal listening devices: monitoring the noise dose...

    Objectives. To monitor listening habits to personal listening devices (PLDs) using a smartphone application and to compare actual listening habits to self-report data. Design....
  • publication

    dedup_wf_001--9a0fa74c3060e99178d156794fd1867b

    Additional file 2: Supplementary Fig. 1. Zyflamend Causes Toxicity and Exacerbates the Effects of Streptozotocin and Adriamycin on ER Stress, Autophagy, and Cell Death in RIN-5F...
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    Exploring the bioactivity potential of <i>Leonotis nepetifolia</i>: phytochem...

    Leonotis nepetifolia (L.) Br. (Lamiaceae) is an African shrub popularly known as ‘cordão-de-frade’ in Brazil, traditionally used to treat infectious diseases, among other uses....
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    Additional file 1: of CAFs secreted exosomes promote metastasis and chemother...

    Figure S1. Isolation and characterization of matched CAFs and counterpart NFs from CRC patients. Figure S2. CAFs promote migration, invasion, and chemotherapy resistance in CRC....
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    Additional file 1: Table S1. of Phase 1/2 study of pacritinib, a next generat...

    Dose adjustment and toxicity management guidelines—non-hematologic toxicities. Table S2 Serious adverse events and deathsa occurring in phase 1 component of the study (n = 43)....
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    Additional file 3: of A prospective phase I dose-escalation trial of stereota...

    Table S1. Target Dose and Volume Data by Individual Patient. CTV- clinical target volume; PTV-I – initial planning target volume; PTF-F – final planning target volume; NR – not...
  • publication

    The Safety and Feasibility of Re-treating Patients with Severe Emphysema with...

    Severe emphysema patients who have been treated with endobronchial coils have been shown to initially benefit, but slowly decline in the years thereafter. Re-treating a patient...