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YY-1224, a terpene trilactone-strengthened Ginkgo biloba, attenuates neurodeg...
Abstract Background Ginkgo biloba has been reported to possess free radical-scavenging antioxidant activity and anti-inflammatory properties. In our pilot study, YY-1224, a... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Six-month adherence to Statin use and subsequent risk of major adverse cardio...
Abstract Background The evidence of adherence to statin decreasing risk of major adverse cardiovascular events (MACEs) is still lack among patients discharged with acute... -
Haploidentical allograft is superior to matched sibling donor allograft in er...
Abstract Background This study compared the effects of pre-transplantation minimal residual disease (pre-MRD) on outcomes in AML patients who underwent human leukocyte... -
Role of mesenchymal stem cells, their derived factors, and extracellular vesi...
Abstract Liver failure is a severe clinical syndrome with a poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as a new intervention in treating liver... -
Characterization and pathogenesis of aerosolized eastern equine encephalitis ...
Abstract Background Licensed antiviral therapeutics and vaccines to protect against eastern equine encephalitis virus (EEEV) in humans currently do not exist. Animal models that... -
A survey of thrombosis experts evaluating practices and opinions regarding ve...
Abstract Background Patients undergoing major abdominal surgery are at high risk for developing venous thromboembolism in the post-operative period. Current evidence-based... -
Glossogyne tenuifolia (Hsiang-ju) extract suppresses T cell activation by inh...
Abstract Background Glossogyne tenuifolia (GT) (Hsiang-ju) is a Chinese herbal medicine previously exhibited an anti-inflammatory activity. This study aimed to investigate the... -
A case report of intravenous posaconazole in hepatic and renal impairment pat...
Abstract Background Invasive aspergillosis (IA) is a fatal infectious complication among immunocompromised patients. Aspergillus terreus, the fourth common species can be... -
A first-in-human phase 1 study of a hepcidin monoclonal antibody, LY2787106, ...
Abstract Background Hepcidin plays a central role in iron homeostasis and erythropoiesis. Neutralizing hepcidin with a monoclonal antibody (mAb) may prevent ferroportin... -
Resistance of Staphylococcus aureus to antimicrobial agents in Ethiopia: a me...
Abstract Background Emergence of antimicrobial resistance by Staphylococcus aureus has limited treatment options against its infections. The purpose of this study was to... -
Analytical characteristics and comparative evaluation of Aptima HCV quant Dx ...
Abstract Background The Aptima HCV Quant Dx assay (Aptima assay) is a fully automated quantitative assay on the Panther® system. This assay is intended for confirmation of... -
Red blood cell transfusion in the resuscitation of septic patients with hemat...
Abstract Background Indications for red blood cell (RBC) transfusion in septic acute circulatory failure remain unclear. We addressed the practices and the prognostic impact of... -
TREatment of ATopic eczema (TREAT) Registry Taskforce: protocol for an intern...
Abstract Background Patients with moderate-to-severe atopic eczema (AE) often require photo- or systemic immunomodulatory therapies to induce disease remission and maintain... -
Cardiovascular risk factors are major determinants of thrombotic risk in pati...
Abstract Background Patients with the lupus anticoagulant (LA) are at an increased risk of thrombotic events, which in turn increase the risk of death. Understanding the... -
SIVA, a target of p53, is downregulated in myelodysplastic syndromes
Abstract Background SIVA is a transcriptional target of p53 that plays a potential role in the development and progression of cancer. In this study, we analyzed SIVA1 and SIVA2...
