-
Differences in reported sepsis incidence according to study design: a literat...
Abstract Background Sepsis and severe sepsis are common conditions in hospital settings, and are associated with high rates of morbidity and mortality, but reported incidences... -
A method for sensitivity analysis to assess the effects of measurement error ...
Abstract Background Measurement error in self-reported dietary intakes is known to bias the association between dietary intake and a health outcome of interest such as risk of a... -
A novel framework for horizontal and vertical data integration in cancer stud...
Abstract Background Recently high-throughput technologies have been massively used alongside clinical tests to study various types of cancer. Data generated in such large-scale... -
DNA methylation and obesity traits: An epigenome-wide association study. The ...
Obesity is associated with increased risk of several diseases and has become epidemic. Obesity is highly heritable but the genetic variants identified by genome-wide association... -
Multiple imputation of multiple multi-item scales when a full imputation mode...
Abstract Background Missing data in a large scale survey presents major challenges. We focus on performing multiple imputation by chained equations when data contain multiple... -
Comparison of weighting approaches for genetic risk scores in gene-environmen...
Abstract Background Weighted genetic risk scores (GRS), defined as weighted sums of risk alleles of single nucleotide polymorphisms (SNPs), are statistically powerful for... -
Methods for designing interventions to change healthcare professionalsâ beh...
Abstract Background Systematic reviews consistently indicate that interventions to change healthcare professional (HCP) behaviour are haphazardly designed and poorly specified.... -
Causal effect of smoking on DNA methylation in peripheral blood: a twin and f...
Abstract Background Smoking has been reported to be associated with peripheral blood DNA methylation, but the causal aspects of the association have rarely been investigated. We... -
The Blessings of Multiple Causes
Causal inference from observational data is a vital problem, but it comes with strong assumptions. Most methods assume that we observe all confounders, variables that affect... -
Clinical determinants of the severity of Middle East respiratory syndrome (ME...
Abstract Background While the risk of severe complications of Middle East respiratory syndrome (MERS) and its determinants have been explored in previous studies, a systematic... -
Ambiguity of non-systematic chemical identifiers within and between small-mol...
Abstract Background A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures,... -
MultiDCoX: Multi-factor analysis of differential co-expression
Abstract Background Differential co-expression (DCX) signifies change in degree of co-expression of a set of genes among different biological conditions. It has been used to... -
Prognostic significance of supradiaphragmatic lymph node metastasis detected ...
Abstract Background Supradiaphragmatic lymph node metastases (SdLNM) are frequently identified using 18F-FDG positron emission tomography/computed tomography (PET/CT) in... -
Elevated serum iron level is a predictor of prognosis in ICU patients with ac...
Abstract Background Accumulation of iron is associated with oxidative stress, inflammation, and regulated cell death processes that contribute to the development of acute kidney... -
Consensus of potential modifiable prognostic factors for persistent pain afte...
Abstract Background Identify and establish consensus regarding potential prognostic factors for the development of chronic pain after a first episode of idiopathic,... -
Status of metered dose inhaler technique among patients with asthma and its e...
Abstract Objective In Asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease... -
Blood groups A and AB are associated with increased gastric cancer risk: evid...
Abstract Background The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent. Methods We used two single... -
Association between KIF1B rs17401966 genetic polymorphism and hepatocellular ...
Abstract Background Several studies have focused on the association between KIF1B rs17401966 polymorphism and susceptibility to hepatitis B virus-related (HBV-related)... -
Continuous hemofiltration improves the prognosis of bacterial sepsis complica...
Abstract Background Liver dysfunction is an independent risk factor for poor prognosis of patients with sepsis. The aim of this study is to evaluate the effects of continuous... -
The gradient test and its finite sample size properties in a conditional maxi...
In asymptotic theory, the gradient test proposed by Terrell is a recent likelihood-based hypothesis testing approach which can be considered as an alternative to the...
