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Integrative assessment of brain and bone invasion in meningioma patients
Abstract Background Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain... -
Patients' preferences for involvement in the decision-making process for trea...
Abstract Background To assess factors associated with the preferred role of the attending ophthalmologist in the decision-making processes before treating diabetic retinopathy... -
The impairment of small nerve fibers in severe sepsis and septic shock
Abstract Background A decrease of small nerve fibers in skin biopsies during the course of critical illness has been demonstrated recently. However, the diagnostic use of skin... -
Homozygous TBC1 domain-containing kinase (TBCK) mutation causes a novel lysos...
Abstract Homozygous mutation of TBC1 domain-containing kinase (TBCK) is the cause of a very recently defined severe childhood disorder, which is characterized by severe... -
Tigecycline in critically ill patients on continuous renal replacement therap...
Abstract Background Tigecycline is a vital antibiotic treatment option for infections caused by multiresistant bacteria in the intensive care unit (ICU). Acute kidney injury... -
Schistosoma haematobium infection morbidity, praziquantel effectiveness and r...
Abstract Background Sub-Saharan Africa carries most of the global burden of schistosomiasis. To optimize disease control and reduce morbidity, precise data are needed for... -
Diazepam and ethanol differently modulate neuronal activity in organotypic co...
Abstract Background The pharmacodynamic results of diazepam and ethanol administration are similar, in that each can mediate amnestic and sedative-hypnotic effects. Although... -
Point-of-care testing for emergency assessment of coagulation in patients tre...
Abstract Background Point-of-care testing (POCT) of coagulation has been proven to be of great value in accelerating emergency treatment. Specific POCT for direct oral... -
Maternal eNOS Deficiency Determines a Fatty Liver Phenotype of the Offspring ...
Maternal environmental factors can impact the phenotype of the offspring via the induction of epigenetic adaptive mechanisms. The advanced fetal programming hypothesis proposes... -
SRF modulates seizure occurrence, activity induced gene transcription and hip...
Abstract A hallmark of temporal lobe epilepsy (TLE) is hippocampal neuronal demise and aberrant mossy fiber sprouting. In addition, unrestrained neuronal activity in TLE... -
Nerve ultrasound characterizes AMN polyneuropathy as inhomogeneous and focal ...
Abstract Objective High-resolution nerve ultrasound (HRUS) is a painless tool to quickly evaluate peripheral nerve morphology in vivo. This study set out to characterize... -
Open-label, multicenter, single-arm phase II DeCOG-study of ipilimumab in pre...
Abstract Background Ipilimumab is an approved immunotherapy that has shown an overall survival benefit in patients with cutaneous metastatic melanoma in two phase III trials. As... -
dedup_wf_001--072e09e2f3a4148cc75d8f03de4f00b4
Impaired semantic knowledge is a characteristic feature of some forms of frontotemporal dementia (FTD), particularly the sporadic disorder semantic dementia. Less is known about... -
Equity in access to health care among asylum seekers in Germany: evidence fro...
Abstract Background Research on inequities in access to health care among asylum-seekers has focused on disparities between asylum-seekers and resident populations, but little... -
Inpatient gradual diagnostics and its relevance for determining treatment str...
Abstract Background Identifying patients who will benefit from spine surgery is still a challenge. This is especially the case when patients’ complaints and medical history,...
