118 items found

Licenses: License Not Specified Groups: figshare Tags: 110309 Infectious Diseases 111714 Mental Health Biochemistry Computational Biology Molecular Biology

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    Tribbles ortholog NIPI-3 and bZIP transcription factor CEBP-1 regulate a Caen...

    Abstract Background Many pathogens secrete toxins that target key host processes resulting in the activation of immune pathways. The secreted Pseudomonas aeruginosa toxin...
  • other

    Dimerized translationally controlled tumor protein increases interleukin-8 ex...

    Abstract Background Histamine releasing factor (HRF) is a unique cytokine known to regulate a variety of immune cells in late allergic reactions. In the previous study, we...
  • other

    The glucocorticoid receptor and cortisol levels in pediatric septic shock

    Abstract Background There is controversy around the prescription of adjunct corticosteroids in patients with fluid-refractory septic shock, and studies provide mixed results,...
  • other

    Invasive DNA elements modify the nuclear architecture of their insertion site...

    Abstract Background The three-dimensional (3D) organization of chromosomes is linked to epigenetic regulation and transcriptional activity. However, only few functional features...
  • other

    Cocaine-mediated induction of microglial activation involves the ER stress-TL...

    Abstract Background Neuroinflammation associated with advanced human immunodeficiency virus (HIV)-1 infection is often exacerbated by chronic cocaine abuse. Cocaine exposure has...
  • dataset

    Sensitivity analysis.

    We used Latin-hypercube sampling to generate 1,000 combinations of the following parameters: basic reproductive number R0, linear scale on interval (1,3); generation time TG,...
  • dataset

    Can terminators be used as insulators into yeast synthetic gene circuits?

    Abstract Background In bacteria, transcription units can be insulated by placing a terminator in front of a promoter. In this way promoter leakage due to the read-through from...
  • dataset

    Drosophila Ref1/ALYREF regulates transcription and toxicity associated with A...

    Abstract RNA-binding proteins (RBPs) are associated with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), but the underlying disease mechanisms remain...
  • dataset

    Integrated analysis of mRNA-seq and miRNA-seq in calyx abscission zone of Kor...

    Abstract Background The objective of this study was to characterize molecular mechanism of calyx persistence in Korla fragrant pear by transcriptome and small RNA sequencing....
  • dataset

    Facile Dehydrogenation of Ethers and Alkanes with a <i>β</i>-Diiminate Pt Fra...

    Reaction between a neutral β-enamineimine ligand (nacnacH) and Me4Pt2(μ-SMe2)2 in diethyl ether results in dehydrogenation of the solvent to form the Pt(II) olefin hydride...
  • dataset

    Additional file 1: of Comparative expression analysis of Phytophthora sojae p...

    Figure S1. Analyses of putative introns. Introns in gene models encoding transcripts XM_0095239513.1, XM_009526562.1, and XM_009526401.1 were validated by PCR, RT-PCR, and...
  • dataset

    The HDAC6/APOBEC3G complex regulates HIV-1 infectiveness by inducing Vif auto...

    Abstract Background Human immunodeficiency virus type 1 (HIV-1) has evolved a complex strategy to overcome the immune barriers it encounters throughout an organism thanks to its...
  • dataset

    dedup_wf_001--aa3e6ae6265db7ffbfcb762afdd4a2ae

    Comprehensive analysis of Long non-coding RNA expression in dorsal root ganglion reveals cell type specificity and dysregulation following nerve injury - Supplemetary Data S....
  • dataset

    The role of SAGA coactivator complex in snRNA transcription

    The general snRNA gene transcription apparatus has been extensively studied. However, the role of coactivators in this process is far from being clearly understood. Here, we...
  • dataset

    dedup_wf_001--c8c6e173e353c06fa7fe66885b52e316

    (a) Four treatments included: A) a healthy tomato ‘receiver’ plant was connected with a neighboring Alternaria solani-challenged tomato ‘donor’ plant through common mycorrhizal...
  • dataset

    eEF1Bγ binds the Che-1 and TP53 gene promoters and their transcripts

    Abstract Background We have previously shown that the eukaryotic elongation factor subunit 1B gamma (eEF1Bγ) interacts with the RNA polymerase II (pol II) alpha-like subunit “C”...
  • dataset

    Regulation of platelet-activating factor-induced interleukin-8 expression by ...

    Abstract Background Platelet-activating factor (PAF) is a potent lipid mediator whose involvement in the onset and progression of atherosclerosis is mediated by, among others,...
  • dataset

    r37980778c78--76977eb0a8efbce78a6dc892cb493fdc

    Taste responses, expressed as tastant/water lick ratios and as a function of stimulus concentration, of GHSR null, (red) and WT (black) to (A) sucrose, (B) DB, (C) NaCl and (D)...