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What helps or hinders the transformation from a major tertiary center to a ma...
Abstract Background Major Trauma Centers (MTCs), as part of a trauma system, improve survival and functional outcomes from injury. Developing such centers from current teaching... -
Development of a promoter shutoff system in <i>Aspergillus oryzae</i> using a...
Promoter shutoff is a general method for analyzing essential genes, but in the fungus Aspergillus oryzae, no tightly repressed promoters have been reported. To overcome the... -
Geriatric support in the emergency department: a national survey in Belgium
Abstract Background Older people in the emergency department (ED) represent a growing population and increasing proportion of the workload in the ED. This study investigated the... -
University students’ awareness of causes and risk factors of miscarriage: a c...
Abstract Background Spontaneous miscarriage is the most common complication of pregnancy, occurring in up to 20% of pregnancies. Despite the prevalence of miscarriage, little is... -
Medical undergraduatesâ perceptions on the end of course assessment in Surg...
Abstract Objective This study reports findings from a feedback assessment conducted among final year medical undergraduates on the end of course assessment in Surgery. A... -
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Correction to: Improved plan quality with automated radiotherapy planning for...
Abstract In the original publication [1] figure legends 2 and 4 have been swapped. The original article was updated to rectify this error. -
Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sc...
Abstract Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are types of major TDP-43 (43-kDa TAR DNA-binding protein) proteinopathy. Cortical... -
Use of diagnostic tests and the appropriateness of the treatment decision in ...
Abstract Background Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
What happened and why? A programme theory-based qualitative evaluation of a h...
Abstract Background There is increasing interest in and demands for partnerships between academia and healthcare practices. Few empirical studies have described the influence of... -
Association between antibiotic consumption and the rate of carbapenem-resista...
Abstract Background This study aimed to investigate the relationship between the rate of carbapenem-resistant Gram-negative bacteria and antibiotic consumption intensity in 153... -
The diagnostic accuracy of the hand-held Raman spectrometer for the identific...
Abstract Background There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to... -
Predicting potential adverse events using safety data from marketed drugs
Abstract Background While clinical trials are considered the gold standard for detecting adverse events, often these trials are not sufficiently powered to detect difficult to... -
Inter-agency collaboration factors affecting multidisciplinary workers’ abili...
Abstract Objectives This study aimed to clarify the factors of successful inter-agency collaboration that affect multidisciplinary workers’ abilities to identify child... -
Development of a prediction model for bacteremia in hospitalized adults with ...
Abstract Background Cellulitis is a common infectious disease. Although blood culture is frequently used in the diagnosis and subsequent treatment of cellulitis, it is a... -
Consumers attitudes and beliefs towards the receipt of antenatal corticostero...
Abstract Background Active participation of consumers in health care decision making, policy and clinical research is increasingly encouraged by governments, influential bodies... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection... -
Prevalence and social determinants of psychological distress among people who...
Abstract Background People who use drugs are at a disproportionately higher risk of mental disorders due to prolonged exposure to psychosocial challenges. However, studies on... -
Pathological complete response due to a prolonged time interval between preop...
Abstract Background Preoperative chemoradiotherapy is the recommended standard of care for patients with local advanced rectal cancer. However, it remains unclear, whether a...
