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Design and methods of the ‘monitoring outcomes of psychiatric pharmacotherapy...
Abstract Background At many outpatient departments for psychiatry worldwide, standardized monitoring of the safety of prescribed psychotropic drugs is not routinely performed in... -
Outcomes in randomised controlled trials in prevention and management of cari...
Abstract Background Inconsistent outcome reporting is one significant hurdle to combining results from trials into systematic reviews. Core outcome sets (COS) can reduce this... -
National survey and point prevalence study of sedation practice in UK critica...
Abstract Background The present study was designed to (1) establish current sedation practice in UK critical care to inform evidence synthesis and potential future primary... -
Inter-agency collaboration factors affecting multidisciplinary workers’ abili...
Abstract Objectives This study aimed to clarify the factors of successful inter-agency collaboration that affect multidisciplinary workers’ abilities to identify child... -
Development of a prediction model for bacteremia in hospitalized adults with ...
Abstract Background Cellulitis is a common infectious disease. Although blood culture is frequently used in the diagnosis and subsequent treatment of cellulitis, it is a... -
Prevalence and correlates of substance use among health care students in Nepa...
Abstract Background Substance use among health care students threatens professional standards and the delivery of quality services, potentially placing the public at risk.... -
Consumers attitudes and beliefs towards the receipt of antenatal corticostero...
Abstract Background Active participation of consumers in health care decision making, policy and clinical research is increasingly encouraged by governments, influential bodies... -
Downstream consequences of diagnostic error in pediatric anaphylaxis
Abstract Background Pediatric anaphylaxis is commonly misdiagnosed in the Emergency Department (ED). We aimed to determine the impact of inaccurate diagnosis on the management... -
Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...
Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection... -
Prevalence and social determinants of psychological distress among people who...
Abstract Background People who use drugs are at a disproportionately higher risk of mental disorders due to prolonged exposure to psychosocial challenges. However, studies on... -
Pathological complete response due to a prolonged time interval between preop...
Abstract Background Preoperative chemoradiotherapy is the recommended standard of care for patients with local advanced rectal cancer. However, it remains unclear, whether a... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Do clerkship schemes effectively improve pharmacy students’ understanding of ...
Abstract Background Clerkship is potentially an effective measure of improving the pharmacy students’ understanding of and attitudes toward pharmaceutical care. This research... -
A multicenter randomized controlled trial of surgery alone or surgery with at...
Abstract Background Postoperative cancer recurrence is a major problem following curative surgery. In a previous retrospective study of lung cancer surgery, we reported that... -
Impact of antibiotic therapy on the development and response to treatment of ...
Abstract Background The gut microbiome impacts the efficacy of immune checkpoint inhibitor (ICI) therapy and the development of ICI-mediated diarrhea and/or colitis (IMDC).... -
Survey indicated that core outcome set development is increasingly including ...
Abstract Background There are numerous challenges in including patients in a core outcome set (COS) study, these can vary depending on the patient group. This study describes... -
Serum progesterone distribution in normal pregnancies compared to pregnancies...
Abstract Background Progesterone is a critical hormone in early pregnancy. A low level of serum progesterone is associated with threatened miscarriage. We aim to establish the... -
Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation t...
Abstract Background Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging... -
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
A Bayesian network meta-analysis on the efficacy and safety of eighteen targe...
Pulmonary arterial hypertension (PAH) can be relieved by pharmacological interventions, especially the targeted drug, which is classified into endothelin receptor antagonist,...
