Applying flexible materials for energy scavenging from ambient mechanical vibrations is a clean energy solution that can help alleviate electrical power demands in portable devices and wearable electronics. This work presents fundamental studies on a flexible ferroelectret polymer with a strong piezoelectric effect and its interface with self-powered and energy storage systems. A single-layered device with a thickness of 80 μm was used for characterizing the device’s output voltage, current, transferred charge, and energy conversion efficiency. The potential capability of harvesting mechanical energy and delivering to system load is demonstrated by integrating the device into a fully integrated power management system. The theory for determining the harvested energy that is ultimately delivered to external electronic loads (or stored in a battery) is discussed. The maximum power delivery is found to be for a 600 MΩ load, which results in a device power density of 14.0 W/m3 for input mechanical forces with a frequency around 2 Hz.