One-Carbon Homologation of Carboxylic Acids via BtCH<sub>2</sub>TMS:  A Safe Alternative to the Arndt−Eistert Reaction

Carboxylic acids are converted into the corresponding homologated acids or esters, using easily available 1-(trimethylsilylmethyl)benzotriazole (1) as a one-carbon synthon. The effectiveness of the reaction has been investigated on six aryl and seven alkyl carboxylic acids.

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PID https://www.doi.org/10.1021/jo0017640.s001
URL https://figshare.com/articles/journal_contribution/One-Carbon_Homologation_of_Carboxylic_Acids_via_BtCH_sub_2_sub_TMS_A_Safe_Alternative_to_the_Arndt_Eistert_Reaction/3688134
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Author Katritzky, Alan R.
Author Zhang, Suoming
Author Hussein, Abdel Haleem Mostafa
Author Fang, Yunfeng
Author Steel, Peter J.
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Collected From figshare
Hosted By figshare
Publication Date 2016-08-19
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Language English
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=r37980778c78::d02956c0fdf59cd8e8671b9b16a5f5b0
Author jsonws_user
Last Updated 26 December 2020, 16:22 (CET)
Created 26 December 2020, 16:22 (CET)