Symplostatin 1:  A Dolastatin 10 Analogue from the Marine Cyanobacterium <i>Symploca </i><i>h</i><i>ydnoides</i>

A new solid tumor selective cytotoxic analogue of dolastatin 10 (1) has been isolated from the marine cyanobacterium Symploca hydnoides, collected near Guam. This metabolite has been assigned the trivial name symplostatin 1 (2). This discovery supports the proposal that many compounds isolated from the seahare Dolabella auricularia, the original source of the dolastatins, are of dietary origin.

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PID https://www.doi.org/10.1021/np980321c.s001
URL https://figshare.com/articles/journal_contribution/Symplostatin_1_A_Dolastatin_10_Analogue_from_the_Marine_Cyanobacterium_i_Symploca_i_i_h_i_i_ydnoides_i_/3734811
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Access Right Open Access
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Author Harrigan, George G.
Author Luesch, Hendrik
Author Yoshida, Wesley Y.
Author Moore, Richard E.
Author Nagle, Dale G.
Author Paul, Valerie J.
Author Mooberry, Susan L.
Author Corbett, Thomas H.
Author Valeriote, Fred A.
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Collected From figshare
Hosted By figshare
Publication Date 2016-08-20
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Language English
Resource Type Other literature type
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=r37980778c78::5a84d4b21e7d7e14ef259585ee52cfe7
Author jsonws_user
Last Updated 26 December 2020, 21:34 (CET)
Created 26 December 2020, 21:34 (CET)