Although the world faces serious environmental, economic, and social challenges, we believe that a combination of science and innovation, effective governance, and public-private collaboration can help to overcome many of them and achieve sustainable development. Numerous government policies are now promoting sustainable management practices, while many people in the business and financial communities view sustainability as a means to reduce long-term risk, enhance competitiveness, and promote social well-being. Advances in science and technology are creating new economic opportunities and producing sustainable solutions, while expanded public access to global data and information is helping to shape business and government policies. Looking ahead, sustainability will be best pursued by building on these trends and encouraging new collaborative initiatives among governments, businesses, and the nonprofit sector. This article is an example of a collaboration that includes government, business, academic, nongovernmental, and international organizations.