Appendix S1. List of laboratories that participate in ARS and contributed data to this analysis. Appendix S2. Geographical distribution of hospitals contributing data to the analysis. Appendix S3. Klebsiella pneumoniae isolates by year and location of hospital in Germany, 2011–2016. Appendix S4. Klebsiella pneumoniae isolates by patient and hospital characteristics in Germany 2011–2016. Appendix S5. Numbers of K. pneumoniae isolates in Germany 2011–2016 included in the analysis stratified by standards used for interpretation of antimicrobial susceptibility testing. Appendix S6. Carbapenem non-susceptibility of K. pneumoniae isolates in Germany 2011–2016 that were tested against all three carbapenems. Appendix S7. Cross-resistance of K. pneumoniae isolates non-susceptible to one carbapenem to other carbapenems restricted to isolates tested against all three carbapenems, Germany 2011–2016. Appendix S8. Sensitivity analyses to investigate the trend of carbapenem non-susceptibility over time. Appendix S9. Proportions of carbapenem non-susceptibility in K. pneumoniae isolates across substrata, Germany 2011–2016. Appendix S10. Uni- and multivariable analyses for carbapenem non-susceptibility of K. pneumoniae isolates stratified by age and sex, Germany 2011–2016. (DOCX 464 kb)