Epidemiology, causes, clinical manifestation and diagnosis, prevention and control of coronavirus disease (COVID-19) during the early outbreak period: A scoping review

Abstract Background The coronavirus disease (COVID-19) has been identified as the cause of an outbreak of respiratory illness in Wuhan, Hubei Province, China beginning in December 2019. As of 31 January 2020, this epidemic had spread to 19 countries with 11 791 confirmed cases, including 213 deaths. The World Health Organization has declared it a Public Health Emergency of International Concern. Methods A scoping review was conducted following the methodological framework suggested by Arksey and O’Malley. In this scoping review, 65 research articles published before 31 January 2020 were analyzed and discussed to better understand the epidemiology, causes, clinical diagnosis, prevention and control of this virus. The research domains, dates of publication, journal language, authors’ affiliations, and methodological characteristics were included in the analysis. All the findings and statements in this review regarding the outbreak are based on published information as listed in the references. Results Most of the publications were written using the English language (89.2%). The largest proportion of published articles were related to causes (38.5%) and a majority (67.7%) were published by Chinese scholars. Research articles initially focused on causes, but over time there was an increase of the articles related to prevention and control. Studies thus far have shown that the virus’ origination is in connection to a seafood market in Wuhan, but specific animal associations have not been confirmed. Reported symptoms include fever, cough, fatigue, pneumonia, headache, diarrhea, hemoptysis, and dyspnea. Preventive measures such as masks, hand hygiene practices, avoidance of public contact, case detection, contact tracing, and quarantines have been discussed as ways to reduce transmission. To date, no specific antiviral treatment has proven effective; hence, infected people primarily rely on symptomatic treatment and supportive care. Conclusions There has been a rapid surge in research in response to the outbreak of COVID-19. During this early period, published research primarily explored the epidemiology, causes, clinical manifestation and diagnosis, as well as prevention and control of the novel coronavirus. Although these studies are relevant to control the current public emergency, more high-quality research is needed to provide valid and reliable ways to manage this kind of public health emergency in both the short- and long-term.

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PID https://www.doi.org/10.1186/s40249-020-00646-x
PID https://www.doi.org/10.6084/m9.figshare.c.4898331.v1
PID https://www.doi.org/10.6084/m9.figshare.c.4898331
URL http://dx.doi.org/10.6084/m9.figshare.c.4898331.v1
URL https://hdl.handle.net/20.500.12663/484
URL http://hdl.handle.net/1765/125720
URL https://doi.org/10.1186/s40249-020-00646-x
URL http://dx.doi.org/10.6084/m9.figshare.c.4898331
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Access Right Open Access
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Author Sasmita Poudel Adhikari
Author Meng, Sha
Author Wu, Yu-Ju
Author Mao, Yu-Ping
Author Ye, Rui-Xue
Author Wang, Qing-Zhi
Author Sun, Chang
Author Sylvia, Sean
Author Rozelle, Scott
Author Raat, Hein
Author Zhou, Huan
Contributor Department of Public Health
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Collected From Datacite; NARCIS; PAHO COVID19
Hosted By Erasmus University Institutional Repository; figshare; PAHO COVID19
Publication Date 2020-03-17
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Country Netherlands
Format application/pdf
Language English
Resource Type Collection; UNKNOWN; Other ORP type
system:type other
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Source https://science-innovation-policy.openaire.eu/search/other?orpId=dedup_wf_001::9d5342dc2a0b5000d63d87663fbf62bc
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Last Updated 20 December 2020, 03:47 (CET)
Created 20 December 2020, 03:47 (CET)