Late outcome of surgical radiofrequency ablation for persistent valvular atrial fibrillation in China: a single-center study

Background Atrial fibrillation (AF) adversely affects surgical outcomes of cardiac valve surgery. Surgical ablation is an effective way to treat valvular AF. The aim of this study was to evaluate the late outcome of surgical radiofrequency ablation and explore the risk factors of AF recurrence in Chinese patients undergoing cardiac valve surgery. Methods Three hundred ninety six consecutive patients with persistent valvular AF were enrolled in this study. They underwent concomitant modified Maze IV and were completed follow-ups. Cox survival regression model was used to screen independent risk factors for predicting late recurrence of AF. Results During the follow-up period of 28 (6 ~ 61) months, AF recurred in 151 patients (38.1%). In multivariate survival regression, factors predictive of AF late recurrence were AF duration, pre-operative serum B-type natriuretic peptide (BNP), pre-operative heart rate and left atrial diameter (LAD), post-operative atrial tachyarrhythmias and AF at discharge. According to receiver operating characteristic curve analysis, the best cutoff values for AF duration, BNP, heart rate and LAD were 66.5 months, 251 pg/ml, 82 beats/min and 67.9 mm, respectively. Conclusions Longer AF duration, larger LAD, higher BNP level and lower heart rate indicated a poor late outcome of surgical radiofrequency ablation in persistent AF patients undergoing cardiac valve surgery. Therefore, indication to radiofrequency ablation should be carefully considered in these patients. Electronic supplementary material The online version of this article (doi:10.1186/s13019-017-0627-z) contains supplementary material, which is available to authorized users.

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PID https://www.doi.org/10.1186/s13019-017-0627-z
PID pmc:PMC5543737
PID pmid:28774344
URL http://link.springer.com/article/10.1186/s13019-017-0627-z
URL http://link.springer.com/content/pdf/10.1186/s13019-017-0627-z.pdf
URL https://doaj.org/toc/1749-8090
URL http://dx.doi.org/10.1186/s13019-017-0627-z
URL https://dx.doi.org/10.1186/s13019-017-0627-z
URL https://cardiothoracicsurgery.biomedcentral.com/articles/10.1186/s13019-017-0627-z
URL https://cardiothoracicsurgery.biomedcentral.com/track/pdf/10.1186/s13019-017-0627-z
URL https://academic.microsoft.com/#/detail/2743251415
URL http://europepmc.org/articles/PMC5543737
URL https://link.springer.com/article/10.1186/s13019-017-0627-z
URL https://www.ncbi.nlm.nih.gov/pubmed/28774344
URL http://europepmc.org/abstract/MED/28774344
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Author Hailong Cao
Author Yunxing Xue
Author Qing Zhou
Author Minggang Yu
Author Chenbin Tang
Author Dongjin Wang
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Collected From Europe PubMed Central; PubMed Central; Datacite; UnpayWall; DOAJ-Articles; Crossref; Microsoft Academic Graph
Hosted By Europe PubMed Central; Journal of Cardiothoracic Surgery
Publication Date 2017-08-03
Publisher Springer Science and Business Media LLC
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Language UNKNOWN
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::700f1829bf6a5104498ac9701f28ed61
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Last Updated 26 December 2020, 07:58 (CET)
Created 26 December 2020, 07:58 (CET)