Figure S1. Correlation between the copy numbers of CpG motifs in 300 bp DNA fragments and IFN-α. Each dot depicts an independent 300 bp DNA fragment amplified from the LC-Plasma genome. Horizontal axes indicate the number of CpG motifs contained in each DNA fragment for A) all fragments, B) low-G + C fragments and C) high-G + C fragments. Vertical axes indicate the relative activity produced by BM-DCs stimulated by each DNA fragment (PPTX 100 kb)