Ultrahigh sensitive optical microangiography for in vivo imaging of microcirculations within human skin tissue beds

In this paper, we demonstrate for the first time that the detailed cutaneous blood flow at capillary level within dermis of human skin can be imaged by optical micro-angiography (OMAG) technique. A novel scanning protocol, i.e. fast B scan mode is used to achieve the capillary flow imaging. We employ a 1310nm system to scan the skin tissue at an imaging rate of 300 frames per second, which requires only ~5 sec to complete one 3D imaging of capillary blood flow within skin. The technique is sensitive enough to image the very slow blood flows at ~4 μm/sec. The promising results show a great potential of OMAG’s role in the diagnosis, treatment and management of human skin diseases.

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PID https://www.doi.org/10.6084/m9.figshare.c.3763031
PID https://www.doi.org/10.6084/m9.figshare.c.3763031.v1
URL http://dx.doi.org/10.6084/m9.figshare.c.3763031.v1
URL http://dx.doi.org/10.6084/m9.figshare.c.3763031
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Author An, Lin
Author Qin, Jia
Author Ruikang K Wang
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Collected From Datacite
Hosted By figshare
Publication Date 2010-01-01
Publisher Figshare
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keyword FOS: Chemical sciences
keyword FOS: Physical sciences
keyword FOS: Biological sciences
keyword FOS: Clinical medicine
system:type other
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Source https://science-innovation-policy.openaire.eu/search/other?orpId=dedup_wf_001::4c802345278f53e762ed0b5e34cf5215
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Last Updated 19 December 2020, 09:29 (CET)
Created 19 December 2020, 09:29 (CET)