Evaluation of dysphagia in different phenotypes of early and idiopathic Parkinsonism

Background Parkinsonism (PD) is a common neurodegenerative disorders into which dysphagia occurs mainly in the late stage and to a lesser extent in an early stage. Diagnosis of dysphagia particularly in early idiopathic Parkinson’s disease (IPD) is important as dysphagia affects the quality of life of patients and most of the patients are unaware of this important symptom. Method Fifty-four patients were enrolled in this study presented with early IPD attending to the outpatient clinic of Sohag University Hospital. All PD patients were assessed by using Unified Parkinson’s Disease Rating Scale (UPDRS) and modified Hoehn and Yahr scale. IPD patients were classified into tremor dominant (TD) and postural instability/gait disorder (PIGD) phenotypes. Swallowing disturbance questionnaire (SDQ) and fiberoptic endoscopic evaluation of swallowing (FEES) were used to evaluate dysphagia. Results Thirty-five percent of patients experienced dysphagia when the patients were questioned, and this percent rises to 40% on using FEES. The results of SDQ were significantly correlated to the results of more accurate FEES. The percentage of dysphagia was higher in patients with PIGD than TD phenotype. Dysphagia was significantly associated with the mean of the Mini-Mental State Examination (MMSE), UPDRS, and modified Hoehn and Yahr scale. Conclusions Dysphagia is a prevalent symptom in early IPD and significantly correlated with Parkinsonism phenotype, UPDRS, and modified Hoehn and Yahr scale. Electronic supplementary material The online version of this article (10.1186/s41983-018-0031-1) contains supplementary material, which is available to authorized users.

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PID https://www.doi.org/10.1186/s41983-018-0031-1
PID pmid:30416335
PID pmc:PMC6208737
URL https://ejnpn.springeropen.com/track/pdf/10.1186/s41983-018-0031-1
URL https://dx.doi.org/10.1186/s41983-018-0031-1
URL http://europepmc.org/articles/PMC6208737
URL https://academic.microsoft.com/#/detail/2898455217
URL http://link.springer.com/content/pdf/10.1186/s41983-018-0031-1.pdf
URL https://ejnpn.springeropen.com/articles/10.1186/s41983-018-0031-1
URL http://link.springer.com/article/10.1186/s41983-018-0031-1
URL https://link.springer.com/article/10.1186/s41983-018-0031-1
URL http://link.springer.com/article/10.1186/s41983-018-0031-1/fulltext.html
URL https://doaj.org/toc/1687-8329
URL https://www.ncbi.nlm.nih.gov/pubmed/30416335
URL http://dx.doi.org/10.1186/s41983-018-0031-1
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Author Mohamed, Al-Amir Bassiouny, 0000-0003-0676-4469
Author Mohamed, Gharib Fawi
Author Elnady, Hassan Mohamed
Author Sayed, Mohamed Abdelmoneim
Author Imam, Ahmed Mamdouh
Author Hassan, Megahed Mohamed
Author Ahmed, Sherihan Rezk
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Collected From Europe PubMed Central; PubMed Central; ORCID; UnpayWall; Datacite; DOAJ-Articles; Crossref; Microsoft Academic Graph
Hosted By Europe PubMed Central; The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Journal The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 54, null
Publication Date 2018-10-24
Publisher Springer Science and Business Media LLC
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Source https://science-innovation-policy.openaire.eu/search/publication?articleId=dedup_wf_001::443bfaabf0d8f7d9f57aac05b964bbf9
Author jsonws_user
Last Updated 26 December 2020, 23:33 (CET)
Created 26 December 2020, 23:33 (CET)