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Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Sel...
Biaryl cyclohexene carboxylic acids were discovered as full and potent niacin receptor (GPR109A) agonists. Compound 1e (MK-6892) displayed excellent receptor activity, good PK... -
MOESM3 of Evaluation of earlier versus later dietary management in long-chain...
Additional file 3. List of excluded studies and reasons. -
Additional file 2: of Associations of the plasma lipidome with mortality in t...
Heatmaps of the differences in the Pearsonâ s r correlation coefficient between survivors and nonsurvivors. Lipids are arranged based on hierarchical clustering using a complete... -
Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Lig...
Design, Radiosynthesis, and Biodistribution of a New Potent and Selective Ligand for in Vivo Imaging of the Adenosine A2A Receptor System Using Positron Emission Tomography -
dedup_wf_001--84a43852e2473f3cc420a04c7dda4e29
Das BMBF-geförderte Projekt OLH-DE hat zum Ziel, konsortiale Modelle für die Förderung von Open Access insbesondere in den Geisteswissenschaften im deutschsprachigen Raum... -
Palladium-Catalyzed Stereoselective Hydrogenolysis of Conjugated 1,1-Dibromo-...
Palladium-Catalyzed Stereoselective Hydrogenolysis of Conjugated 1,1-Dibromo-1-alkenes to (Z)-1-Bromo-1-alkenes. An Application to Stepwise and One-Pot Synthesis of Enediynes... -
r37980778c78--d8e4a30ef29b2537232c58a8fd792bdf
An enantio- and diastereoselective stepwise cyclization of polyprenoids induced by Lewis acid-assisted chiral Brønsted acids (chiral LBAs) and achiral LBAs is described. In... -
dedup_wf_001--7f58fe82b0f087fbb7d76245cc7eef1f
Konzeptuelle Überlegungen für den nachhaltigen Umgang mit Dokumenten der öffentlichen Hand gezeigt am Beispiel eines Open Access Repositorium der österreichischen Raumplanung.... -
Antitumor activity of saponin isolated from the sea cucumber, <i>holothuria a...
The present investigation attempted study the potential use of the Holothuria arenicola saponin (HaS) against Ehrlich Ascites Carcinoma (EAC) tumor model in female Swiss albino... -
dedup_wf_001--9e12a6f29630ce8db912a0f0cf97da60
Figure S1. Nsun5 deficiency impairs development of cerebral cortex. A Representative images of cerebral cortex stained with toluidine blue in WT mice and heterozygous deletion... -
dedup_wf_001--cedafc998d1fc5debcd248d1a74f7628
Figure S1. Schematic of drug-inducible sgRNA expression lentiviral vectors. Figure S2. Nucleotide sequence presentation of the DOX- and IPTG-inducible U6 promoter variants used... -
Labeling System
Als Linked Open Data wird die direkte Vernetzung von frei verfügbaren Daten im Internet bezeichnet. Aufgrund der ständig wachsenden Datenmenge ergeben sich für die... -
Synthesis and Structures of Crystalline Lithium, Sodium, Potassium, and Magne...
The paper deals with metal complexes of the silylmethyl ligands [CH(SiMe3){SiMe3-n(OMe)n}]- (n = 1, 2), [CH(SiMe3)(SiMe2Ph)]-, and [CH(SiMe2OMe)2]-. Treatment of the precursor... -
Lithiation and Li-Doped Effects of [5]Cyclacene on the Static First Hyperpola...
On the basis of tubiform [5]cyclacene, a new multilithium salt Li5-[5]cyclacene and a new electride Li−Li5-[5]cyclacene are designed in theory. As five Li atoms substituting the... -
Leading scientists towards openness
Some questions, ideas and prompts for our session at science online 2013 -
r37980778c78--b00202cc979a167d00f8cfd4a226a806
Engagement of toll-like receptors serve to link innate immune responses with adaptive immunity and can be exploited as powerful vaccine adjuvants for eliciting both primary and... -
Additional file 1: of Metformin restores electrophysiology of small conductan...
Table S1. Raw data of blood glucose level. Table S2. Raw data of fibrotic area. Table S3. Raw data of western blotting detection of the expressions of KCa2.1, KCa2.2 and KCa2.3.... -
Cross-Talk between Lung and Systemic Circulation during Carbon Nanotube Respi...
Nanotechnology is an emerging field that demands urgent development of adequate toxicology and risk assessment. The previous experimental data on carbon nanotube respiratory... -
MOESM3 of Putative virulence factors of Corynebacterium pseudotuberculosis FR...
Additional file 3. Homologous proteins of C. pseudotuberculosis FRC41 putative virulence factor SodC in CMNR microorganism and mammalians. -
r37980778c78--d869d6051fac6bb3f5659a3c6d4628b7
Nine C-10 non-acetal derivatives of the natural trioxane artemisinin (1) were prepared as dimers using some novel chemistry. As designed, each dimer was stable chemically. C-10...
