75 items found

Types: other Groups: figshare Tags: Genetics Science Policy

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    Data quality and feasibility of the Experience Sampling Method across the spe...

    Abstract Background Due to a number of methodological advantages and theoretical considerations, more and more studies in clinical psychology research employ the Experience...
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    The impact of MTHFR 677C → T risk knowledge on changes in folate intake: find...

    © 2016 The Author(s). Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License...
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    Peripheral neuropathy in metachromatic leukodystrophy: Current status and fut...

    Abstract Metachromatic leukodystrophy (MLD) is an autosomal recessively inherited metabolic disease characterized by deficient activity of the lysosomal enzyme arylsulfatase A....
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    Development of an infant feeding core outcome set for childhood obesity inter...

    Abstract Background Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated...
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    Activation of chloramphenicol biosynthesis in Streptomyces venezuelae ATCC 10...

    Abstract Background Streptomyces venezuelae ATCC 10712 produces antibiotics chloramphenicol (Cml) and jadomycin (Jad) in response to nutrient limitation and ethanol shock (ES),...
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    Influence of genetic variants on toxicity to anti-tubercular agents: a system...

    MR is supported partly by Liverpool Reviews and Implementation Group (LRiG), based on funding from the National Institute for Health Research Health Technology Assessment...
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    The gradient test and its finite sample size properties in a conditional maxi...

    In asymptotic theory, the gradient test proposed by Terrell is a recent likelihood-based hypothesis testing approach which can be considered as an alternative to the...
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    Two subphenotypes of septic acute kidney injury are associated with different...

    Abstract Background The pathophysiology of septic acute kidney injury is inadequately understood. Recently, subphenotypes for...
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    Self-monitoring of health data by patients with a chronic disease: does disea...

    Background: There is a growing emphasis on self-monitoring applications that allow patients to measure their own physical health parameters. A prerequisite for achieving...
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    Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...

    Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory...
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    A global sensitivity analysis approach for morphogenesis models

    Abstract Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as...
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    Comparative and selection sweep analysis of CNV was associated to litter size...

    This study aims to identify the relative Copy number variation (CNV) associated with the litter size of Dazu black goats based on the unpublished CNV analytical results of our...
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    Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...

    Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been...
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    Scaling up strategies of the chronic respiratory disease programme of the Eur...

    Abstract Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care...
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    Assessment of fatigability in patients with spinal muscular atrophy: developm...

    Background: Fatigability has emerged as an important dimension of physical impairment in patients with Spinal Muscular Atrophy (SMA). At present reliable and valid outcome...
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    An inventory of collaborative medication reviews for older adults - evolution...

    Abstract Background Collaborative medication review (CMR) practices for older adults are evolving in many countries. Development has been under way in Finland for over a...
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    Surviving critical illness, what is next?: an expert consensus statement on p...

    Abstract Background The study objective was to obtain consensus on physical therapy (PT) in the rehabilitation of critical illness survivors after hospital discharge. Research...
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    Qualitative study exploring the phenomenon of multiple electronic prescribing...

    BACKGROUND: A previous census of electronic prescribing (EP) systems in England showed that more than half of hospitals with EP reported more than one EP system within the same...
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    Mobility assessment of a rural population in the Netherlands using GPS measur...

    Background: The home address is a common spatial proxy for exposure assessment in epidemiological studies but mobility may introduce exposure misclassification. Mobility can be...
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    Crowdsourced direct-to-consumer genomic analysis of a family quartet

    Abstract Background We describe the pioneering experience of a Spanish family pursuing the goal of understanding their own personal genetic data to the fullest possible extent...