724 items found

Licenses: License Not Specified Tags: Cell Biology Genetics Pharmacology Groups: figshare Open Access Types: publication

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  • publication

    Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...

    Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a...
  • publication

    Additional file 1: of Successful contemporary reverse controlled antegrade an...

    Timeline of the Clinical Course. (DOCX 15 kb)
  • publication

    The imprint of X-ray photoevaporation on the orbital distribution of giant pl...

    Recent exoplanet surveys have highlighted the existence of an impressive diversity of planetary systems, raising the question of how systems similar to our own can form and...
  • publication

    <i>N</i>-Phenylphenylglycines as Novel Corticotropin Releasing Factor Recepto...

    Screening of a computationally designed synthetic library led to the discovery of the N-phenylphenylglycines (NPPGs) as a novel class of human corticotropin releasing factor...
  • publication

    dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7

    A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary...
  • publication

    r37980778c78--56fcee8741a21a8729fa2db393bd30b0

    Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The...
  • publication

    Additional file 1: of Effect of 90Sr internal emitter on gene expression in m...

    Manual cell counts for lymphocytes from blood smears. (PDF 89 kb)
  • publication

    Effect of a 17α-(3-Hydroxypropyl)-17β-acetyl Substituent Pattern on the Gluco...

    Replacing the 17α-acetoxy substituent in an antiprogestational 17β-acetyl-11β-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor...
  • publication

    MOESM1 of Neural hyperactivity in the amygdala induced by chronic treatment o...

    Additional file 1: Table S1. The effect of analgesic exposure on CSD anxiety behaviors. Table S2. The effect of analgesic exposure on CSD generation. Table S3. Number of...
  • publication

    Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...

    A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and...
  • publication

    Integrated Comparison of Drug-Related and Drug-Induced Ultra Performance Liqu...

    The biochemical variations induced in human primary hepatocyte cultures by reference activators of xenoreceptor CAR (NR1I3) and PXR (NR1I2), i.e., rifampicin, phenobarbital, and...
  • publication

    dedup_wf_001--1267f88dc9dab84c2df43cf8151d0f07

    Mass spectrometry analysis of rhSIRPA protein. Table S2. Mass spectrometry analysis of calibrator from SIRPA ELISA kit (Cusabio). Table S3. Mass spectrometry analysis of...
  • publication

    1,2,4-Triazol-3-yl-thiopropyl-tetrahydrobenzazepines:  A Series of Potent and...

    The discovery of new highly potent and selective dopamine D3 receptor antagonists has recently permitted characterization of the role of the dopamine D3 receptor in a wide range...
  • publication

    r37980778c78--45c77806280e278526960e808d2b7b2b

    Electrolysis of benzylthiocyanate, benzyl chloride, p-methylbenzyl chloride, p-methoxybenzyl chloride, or toluene in acetonitrile, at platinum electrodes in a two compartments...
  • publication

    Novel 2,3-Dihydrobenzofuran-2-carboxylic Acids:  Highly Potent and Subtype-Se...

    The design and synthesis of a novel class of 2,3-dihydrobenzofuran-2-carboxylic acids as highly potent and subtype-selective PPARα agonists are reported. Systematic study of...
  • publication

    dedup_wf_001--6d861b369baefc69c3e80ffc8d3b1880

    Example file showing the representation of all molecular interaction data from a single publication (PMID: 26919541) in PSI-MI XML3.0.0 â note, includes use case 1.3Â k, rewrite...
  • publication

    Detoxil Burn Review: Detoxil Burn Ingredients | Detoxil Burn 10.0 Omega Formula

    Detoxil Burn 10.0 Omega Formula is a nutritional fat loss supplement that is designed to help to melt away your unwanted pounds of your body. The Detoxil burn Omega formula is...
  • publication

    MOESM4 of Peripheral neuropathy in metachromatic leukodystrophy: current stat...

    Additional file 4: Table S3. Ongoing clinical trials on metachromatic leukodystrophy (MLD). A summary of the ongoing clinical trials on treatment for metachromatic...
  • publication

    dedup_wf_001--805648891f5baefe3b11eb5f89b44dd1

    Figure S5. External eye quantification scale for (GR)36 animals. For quantification of the enhancement effects of increased expression of HSF in the eye, (GR)36 animals received...
  • publication

    dedup_wf_001--eff8f5bc9de3d863386184c6fe5b1db4

    Additional file 1: Figure S1. The secondary lymphoid tissues other than GALT appear normal in β7-F185A KI and β7-KO mice. Representative histological sections of the peripheral...