220 items found

Types: publication Tags: 110309 Infectious Diseases Developmental Biology Genetics Immunology Science Policy

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  • publication

    Etomidate decreases adrenal gland apoptosis and necrosis associated with hemo...

    Purpose: Evaluate if etomidate modulates adrenal apoptosis and if this influences the development of critical illness-related corticosteroid insufficiency (CIRCI) in hemorrhagic...
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    Additional file 1: of Prognosis of nonspecific interstitial pneumonia correla...

    Table S1. The prognostic factors study with multivariate analysis. (DOCX 406 kb)
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    dedup_wf_001--2dbd902d32852b0bf02ba26d8096df2d

    Canonical Pathway enrichment by IPA®. DEGs as detected in the following pairwise comparisons were analyzed by IPA to identify canonical pathways highly represented within each...
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    Additional file 2: of Safety, tolerability, pharmacokinetics, and pharmacodyn...

    Selection criteria: sufficient organ function (DOCX 13 kb)
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    Additional file 2: of Severe asthma features in children: a caseâ control on...

    Criteria for inclusion of children with severe asthma and non-severe persistent asthma. (PDF 25Â kb)
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    MOESM4 of Having concomitant asthma phenotypes is common and independently re...

    Additional file 4: Table S3. Weighted percentages and comparisons of asthma-related outcomes among subjects with a single asthma phenotype versus: non-classified, and specific...
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    MOESM5 of The putative β-glucosidase BGL3I regulates cellulase induction in T...

    Additional file 5. Analysis of transcription levels of transcription factors. (A) transcription factor xyr1, (B) transcription factor cre1, (C) transcription factor ace1, (D)...
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    Additional file 5: of RNA helicase p68 deploys β-catenin in regulating RelA/...

    Table S1. List of primers used in the study. (DOCX 19 kb)
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    Additional file 1 of Household fuel use and adverse pregnancy outcomes in a G...

    Additional file 1: Table S1. Definitions of Adverse Pregnancy Outcomes. Figure S1. Flowchart Of Those Included From Original Cohort. Table S3. original cohort descriptive data...
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    dedup_wf_001--c69b1a514da597a696e7583221c94ce2

    Additional file 1: Figure S1. Visceral fat accumulation and prevalence of sarcopenia, low skeletal muscle mass, and weak grip strength (men, women). The subjects were divided...
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    MOESM3 of Putative virulence factors of Corynebacterium pseudotuberculosis FR...

    Additional file 3. Homologous proteins of C. pseudotuberculosis FRC41 putative virulence factor SodC in CMNR microorganism and mammalians.
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    dedup_wf_001--3d32c44abc979306063316e35de1b5e0

    In biosimilar development, often multiple endpoints within a study, multiple doses and routes of administration or multiple studies in different populations are considered....
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    dedup_wf_001--8fb97c9a9829fef2614b5e6489c723c6

    Serum autoantibody profiles of PM/DM patients in this study. (DOCX 51Â kb)
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    Additional file 4: of XGR software for enhanced interpretation of genomic sum...

    Justification of the 90 and 50% criteria used to remove redundant terms resulting from enrichment analysis. The pathway enrichment analysis is applied to the same set of genes...
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    Additional file 2: Figure S1. of The face of Ebola: changing frequency of hae...

    Forest plots of the meta-analyses of the relative frequencies of conjunctival (a), nasal (b) and gingival (c) bleeding among EVD patients. Note the differences between Central...
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    Additional file 2: of Correlation between global methylation level of periphe...

    Table S2. Assessment of association between HP infection and global methylation levels with/without adjustment with life-style factors, folate intake and serum CRP...
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    MOESM1 of Sprouty Is a Negative Regulator of Transforming Growth Factor β-In...

    Supplementary material, approximately 999 KB.
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    Economic issues to consider for gene drives

    We examine four economic issues regarding gene drive applications made possible by gene editing technologies. First, whether gene drives are self-sustaining or self-limiting...
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    Additional file 4: of Associating expression and genomic data using co-occurr...

    Figure S4. Survival characteristics of the patients that have a mutation in TP53 and low expression in ESR1 (TP53-ESR1, green). The survival curve is compared against a group...
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    Associations between skin rash, treatment outcome, and single nucleotide poly...

    Purpose: To study the associations between development of moderate to severe skin rash, clinical outcome, and single nucleotide polymorphisms (SNPs) in candidate genes in head...