1,051 items found

Types: publication Tags: Biochemistry Cancer Pharmacology

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  • publication

    Identifying research gaps in substance use disorder: A systematic methodology...

    Background: This paper presents a new methodology for identifying and prioritizing research gaps, contributing to the nascent literature on systematic ways to identify research...
  • publication

    dedup_wf_001--c72cf95bcfb67bf41b2d168df879c108

    Lightning talk presented at Collaborations Workshop 2019 organised by the Software Sustainability Institute.
  • publication

    r37980778c78--8cb26c1184e90ec8981a194d23b14ab8

    The reaction kinetics of chlorine atoms with a series of partially fluorinated straight-chain alcohols, CF3CH2CH2OH (1), CF3CF2CH2OH (2), CHF2CF2CH2OH (3), and CF3CHFCF2CH2OH...
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    dedup_wf_001--d7a3cc37eaf776708e5627541ec8b692

    Table S2. Primers used in the qRT-PCR assay. (DOCX 13 kb)
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    r37980778c78--8a4bca988b69036b2c1e00675f6dedf8

    Structural determination of crystalline powders, especially those of complex materials, is not a trivial task. For non-stoichiometric guest−host materials, the difficulty lies...
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    Research articleHemolysis in human erythrocytes by <i>Clostridium perfringens...

    Epsilon-toxin (ETX) is produced by types B and D strains of Clostridium perfringens, which cause fatal enterotoxaemia in sheep, goats and cattle. Previous studies showed that...
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    1-Alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: Development and Characteriz...

    A new series of 1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines was designed, synthesized, and characterized in radioligand binding and functional assays at A2B adenosine...
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    dedup_wf_001--728a1d9e05c2d3fb4716150e063e5d7f

    Polybrominated diphenyl ethers (PBDE) are flame retardants found in many industrial components, such as furniture foam, consumer electronics, plastics, and textiles and levels...
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    Discovery of 1-[9-(4-Chlorophenyl)-8-(2-chlorophenyl)-9<i>H</i>-purin-6-yl]-4...

    We report the structure−activity relationships, design, and synthesis of the novel cannabinoid type 1 (CB1) receptor antagonist 3a (CP-945,598). Compound 3a showed subnanomolar...
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    Additional file 3: of HDAC2 depletion promotes osteosarcomaâ s stemness both ...

    Table S2. Distribution of Sox2, OCT4 and Nanog stemness markers in Saos2 and MG63 cells after drug treatments. (DOC 32 kb)
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    Additional file 7: Table S1. of Blockade of autophagy reduces pancreatic canc...

    List of antibodies used in this study. (DOCX 20Â kb)
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    Crosslinked nanogel-based porous hydrogel as a functional scaffold for tongue...

    Surgical resection in tongue cancer can impair speech and swallowing, reducing quality of life. There is a need for biomaterials that can regenerate tongue muscle tissue...
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    Autofluorescence of Condensed Heme Aggregates in Malaria Pigment and Its Synt...

    The condensed crystalline phase of iron(III) protoporphyrin IX either isolated from parasite culture as malaria pigment (hemozoin) or synthetic equivalent hematin anhydride...
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    Synthesis and Structure−Activity Relationships of a New Series of Retinoid-Re...

    Atypical retinoids (AR) represent a class of proapoptotic agents with promising potential in the treatment of neoplastic diseases. In the present work...
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    Additional file 3: of Pancreatic cancer as a sentinel for hereditary cancer p...

    Table S4. Is a list of reports/genes used for meta-analysis. Table S5. is the values that were used to create Fig. 3. (DOCX 34 kb)
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    Synthesis, molecular docking, antimicrobial, antiquorum-sensing and antiproli...

    New series of pyrazolo[3,4-b]pyridines were prepared and evaluated for antimicrobial activity toward six selected microorganisms. Compounds 2a, 3b, 3d and 3e exhibited good...
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    Cytotoxic flavonoids from the fruits of <i>Derris indica</i>

    Chemical investigation of the ethyl acetate extract from the fruits of Derris indica has led to the isolation of a new furanoflavonoid derivative, 4′-hydroxypinnatin (1), and...
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    r37980778c78--f3f7c1816929e601f20558f37c53faac

    Molecular hydrogen adds to aliphatic and aromatic alkynylstannanes in the presence of a ruthenium catalyst, pushing the stannyl group to the adjacent carbon atom to give...
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    Hydrocarbon Activation via Reversible 1,2-RH-Elimination from (<sup>t</sup>Bu...

    Hydrocarbyl complexes, (tBu3SiNH)3ZrR (1-R), were prepared via metatheses of (tBu3SiNH)3ZrCl (1-Cl) with RMgX or RLi (R = Me, Et, Cy, CH2Ph, allyl, CHCH2, Ph, CH2tBu, C⋮CPh,...
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    r37980778c78--4816a1a6e4d6a60d570bdbb6d414ddf1

    In a previous study, we identified (−)-N-[(1R,4S,5S,7R)-5-(3-hydroxyphenyl)-4-methyl-2-(3-phenylpropyl)-2-azabicyclo[3.3.1]non-7-yl]-3-(1-piperidinyl)propanamide (5a, KAA-1) as...