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Defining the clinical pathway in cochrane diagnostic test accuracy reviews
Abstract Background The value of a medical test depends on the context in which it might be used. Ideally, questions, results and conclusions of a diagnostic test accuracy (DTA)... -
A systematic review to investigate the measurement properties of goal attainm...
Abstract Background One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be... -
The COMET Handbook: Version 1.0
Abstract The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to... -
Rational and design of an individual participant data meta-analysis of spinal...
Abstract Background Chronic low back pain (LBP) is the leading cause of pain and disability, resulting in a major socioeconomic impact. The Cochrane Review which examined the... -
The influence of pregnancy on the pharmacokinetic properties of artemisinin c...
Abstract Background Pregnancy has been reported to alter the pharmacokinetic properties of anti-malarial drugs, including the different components of artemisinin-based... -
SCORE-IT (Selecting Core Outcomes for Randomised Effectiveness trials In Type...
Abstract Background Outcomes measured in clinical trials should be meaningful to patients, healthcare professionals and researchers, yet there is heterogeneity in the outcomes...
