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Parental smoke exposure and the development of nicotine craving in adolescent...
Abstract Background Among adolescent novice smokers, craving is often the first, and is the most reported, symptom of nicotine dependence. Until now, little has been known about... -
Additional file 1 of A1 reactive astrocytes and a loss of TREM2 are associate...
Additional file 1: Supplementary-Figure 1. Early vascular amyloid deposition in a transgenic mouse model for Familial Danish Dementia (Tg-FDD). Thio-S staining of brain from... -
Additional file 2: of Trends in treatment with antipsychotic medication in re...
Overview of the studies included in the scoping review. ADL = Activities of Daily Living; BPSD = Behavioural and Psychological Symptoms of Dementia; MDDAS = Multi-Dimensional... -
Long-term prenatal exposure to paracetamol is associated with DNA methylation...
Abstract Background Epidemiological studies have shown that long-term exposure to paracetamol during pregnancy is associated with attention-deficit/hyperactivity disorder... -
Additional file 4: Table S1. of Bapineuzumab for mild to moderate Alzheimer’s...
Change from baseline to week 78 by MMSE score at baseline (ApoE ε4 carriers and noncarriers). Table showing analysis of ADAS-Cog/11 and DAD scores by disease severity. (DOCX 14 kb) -
Efficient RT-QuIC seeding activity for α-synuclein in olfactory mucosa sample...
Abstract Background Parkinson’s disease (PD) is a neurodegenerative disorder whose diagnosis is often challenging because symptoms may overlap with neurodegenerative... -
Suicide prevention and depression apps’ suicide risk assessment and managemen...
Abstract Background There are an estimated 800,000 suicides per year globally, and approximately 16,000,000 suicide attempts. Mobile apps may help address the unmet needs of... -
Additional file 1: Figure S1. of Autophagic and lysosomal defects in human ta...
Tau pathology observed with the Tau/pS422 antibody. a-f Immunofluorescence staining against hyperphosphorylated tau (Tau/pS422) in human brain samples. Intense immunoreactivity... -
The OPTIMIZE patient- and family-centered, primary care-based deprescribing i...
Abstract Background Most individuals with dementia or mild cognitive impairment (MCI) have multiple chronic conditions (MCC). The combination leads to multiple medications and... -
ADHD-related sex differences in fronto-subcortical intrinsic functional conne...
Abstract Background Attention-deficit/hyperactivity disorder (ADHD) is associated with atypical fronto-subcortical neural circuitry and heightened delay discounting, or a... -
Additional file 4: of NF-κB/c-Rel deficiency causes Parkinson’s disease-like ...
Figure S4. Alpha-synuclein in c-rel-/- mice is aggregated and phosphorylated. (a-f) Representative photomicrographs showing proteinase K-resistant α-synuclein in DMV, LC and SN... -
Early development of infants with neurofibromatosis type 1: a case series
Abstract Background Prospective studies of infants at familial risk for autism spectrum disorder (ASD) have yielded insights into the earliest signs of the disorder but... -
Shared genetic influences between dimensional ASD and ADHD symptoms during ch...
Abstract Background Shared genetic influences between attention-deficit/hyperactivity disorder (ADHD) symptoms and autism spectrum disorder (ASD) symptoms have been reported.... -
Premorbid physical activity is modestly associated with gait independence aft...
Abstract Background Regaining physical function after a stroke is important for independence and for performing activities of daily living. Particularly, cerebrovascular... -
Assessing cognition and daily function in early dementia using the cognitive-...
Abstract Background The cognitive-functional composite (CFC) was designed to improve the measurement of clinically relevant changes in predementia and early dementia stages. We... -
From provocation to aggression: the neural network
Abstract Background In-vivo observations of neural processes during human aggressive behavior are difficult to obtain, limiting the number of studies in this area. To address... -
Peripheral nerve injury-induced alterations in VTA neuron firing properties
Abstract The ventral tegmental area (VTA) is one of the main brain regions harboring dopaminergic (DA) neurons, and plays important roles in reinforcement and motivation. Recent... -
Measuring the well-being of people with dementia: a conceptual scoping review
Abstract Background Enabling people with dementia to ‘live well’ is a policy and research priority in many countries. However, instruments for measuring outcomes of psychosocial... -
Effects of high-frequency transcranial magnetic stimulation on functional per...
Abstract Background Repetitive transcranial magnetic stimulation (rTMS) has been investigated as a new tool in neurological rehabilitation of individuals with spinal cord injury... -
Neuropsychological profiles of adult bipolar disorder patients with and witho...
Abstract Background Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool...
