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Condition-specific promoter activities in Saccharomyces cerevisiae
Abstract Background Saccharomyces cerevisiae is widely studied for production of biofuels and biochemicals. To improve production efficiency under industrially relevant... -
New-onset non-infectious pulmonary manifestations among patients with systemi...
Abstract Objective The objective was to estimate the incidence of lung disease among patients with systemic lupus erythematosus (SLE). Methods Using Swedish register data, we... -
The contribution of culturomics to the repertoire of isolated human bacterial...
Abstract After a decade of research and metagenomic analyses, our knowledge of the human microbiota appears to have reached a plateau despite promising results. In many studies,... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Transcriptionally promiscuous "blurry" promoters in Tc1/mariner transposons a...
Abstract Background We have recently described a peculiar feature of the promoters in two Drosophila Tc1-like elements, Bari1 and Bari3. The AT-richness and the presence of weak... -
Selection of reliable reference genes for the normalisation of gene expressio...
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles... -
Diabetic retinopathy is associated with the presence and burden of subclinica...
Abstract Background Cardiovascular (CV) disease due to atherosclerosis is a major cause of morbidity and mortality in adult patients with diabetes, either type 1 or type 2... -
Preparing the next generation of genomicists: a laboratory-style course in me...
Abstract The growing gap between the demand for genome sequencing and the supply of trained genomics professionals is creating an acute need to develop more effective genomics... -
Complex microseismic activity and depth-dependent stress field changes in Wak...
Abstract We examined the spatial relationship between seismicity and upper crustal structure in the Wakayama region, northwestern Kii Peninsula, Japan, by investigating... -
Association between empirically derived dietary patterns with blood lipids, f...
Abstract Background Dietary patterns (DPs) in India are heterogenous. To date, data on association of indigenous DPs in India with risk factors of nutrition-related... -
Distinct core promoter codes drive transcription initiation at key developmen...
Abstract Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key... -
Origin, evolution and conservation of the honey bees from La Palma Island (Ca...
Genetic studies have shown a significant hybridization of local populations of Apis mellifera in the Canary Islands, as a consequence of queen importation. Since La Palma Island... -
MiR-1-3p that correlates with left ventricular function of HCM can serve as a...
Abstract Background MicroRNAs (miRNAs) are non-coding RNAs that function as regulators of gene expression and thereby contribute to the complex disease phenotypes. Hypertrophic... -
Sucroferric oxyhydroxide decreases serum phosphorus level and fibroblast grow...
Abstract Objective Sucroferric oxyhydroxide, a novel iron-based phosphate-binder, has been shown to have beneficial effects in lowering serum phosphorus levels and improving... -
Capturing the diversity of the human gut microbiota through culture-enriched ...
Abstract Background The human gut microbiota has been implicated in most aspects of health and disease; however, most of the bacteria in this community are considered... -
The human disease network in terms of dysfunctional regulatory mechanisms
Abstract Background Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug... -
A food-grade expression system for d-psicose 3-epimerase production in Bacill...
Abstract Background Food-grade expression systems require that the resultant strains should only contain materials from food-safe microorganisms, and no antibiotic resistance... -
Draft genome sequence of Halomonas meridiana R1t3 isolated from the surface m...
Abstract Members of the gammaproteobacterial genus Halomonas are common in marine environments. Halomonas and other members of the Oceanospirillales have recently been... -
Blood groups A and AB are associated with increased gastric cancer risk: evid...
Abstract Background The association of ABO blood groups with gastric cancer risk was proposed decades ago, but the results have been inconsistent. Methods We used two single... -
Characterization of a strong and constitutive promoter from the Arabidopsis s...
Abstract Background Transgenic technology has become an important technique for crop genetic improvement. The application of well-characterized promoters is essential for...
