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A novel framework for horizontal and vertical data integration in cancer stud...
Abstract Background Recently high-throughput technologies have been massively used alongside clinical tests to study various types of cancer. Data generated in such large-scale... -
Higher education in Gerodontology in European Universities
Abstract Background The rapid aging of the European population and the subsequent increase in the oral care needs in older adults necessitates adequate training of dental... -
CellTag Indexing: genetic barcode-based sample multiplexing for single-cell g...
Abstract High-throughput single-cell assays increasingly require special consideration in experimental design, sample multiplexing, batch effect removal, and data... -
Contributing factors to severe complications after liver resection: an aggreg...
Abstract Background The aggregate root cause analysis (AggRCA) was designed to improve the understanding of system vulnerabilities contributing to patient harm, including... -
Rice WRKY11 Plays a Role in Pathogen Defense and Drought Tolerance
Abstract Background Plants are frequently subjected to abiotic and biotic stresses, and WRKY proteins play a pivotal role in the response to such stress. OsWRKY11 is induced by... -
Bidirectional associations between mothers’ feeding practices and child eatin...
Abstract Background This study examined bidirectional relationships between maternal feeding practices and child food responsiveness and satiety responsiveness from 2 to 5... -
Repeated social defeat promotes persistent inflammatory changes in splenic my...
Abstract Background Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the... -
Integrative assessment of brain and bone invasion in meningioma patients
Abstract Background Various prognostic factors have been suggested in meningioma patients including WHO grading, brain invasion and bone involvement, for instance. Brain... -
Transcriptome analysis reveals new microRNAs-mediated pathway involved in ant...
Abstract Background 337S is a novel bi-pole-photo-thermo-sensitive genic male sterile line in wheat, and sensitive to both long day length/high temperature and short day... -
Technical and environmental characterization of dual-purpose cattle farms and...
Abstract There are few reports on dual-purpose cattle systems characterization in Latin America and Colombia based on large datasets. This limits our understanding of their... -
Reduced DNA methylation of the oxytocin receptor gene is associated with obse...
Abstract Background Oxytocin is an important neuromodulator involved in cognition and socio-emotional processing that exerts its central activities via oxytocin receptors.... -
One–shot phase stepping with a pulsed laser and modulation of polarization: a...
For applications involving time varying optical phase distributions, fast cameras and/or pulsed lasers have to be used. To apply phase–shifting interferometry techniques (PSI)... -
Association of CYP2A6 gene deletion with cancers in Japanese elderly: an auto...
Abstract Background CYP2A6 is an enzyme involved in oxidation of a number of environmental chemicals, including nicotine, pro-carcinogenic nitrosamines and polycyclic aromatic... -
Objectively measured physical activity in population-representative parent-ch...
Abstract Background Evidence for the context-specific influence of parental modelling on physical activity (PA) in childhood remains inconclusive. This nationwide Swiss study... -
Disease causing poverty: adapting the Onyx and Bullen social capital measurem...
Abstract Background Disease-causing poverty is a serious problem in rural China, where social capital can mediate the disease—poverty relationship. However, there is no... -
Evaluating parents’ decisions about next-generation sequencing for their chil...
Abstract Background Using next-generation sequencing (NGS) in newborn screening (NBS) could expand the number of genetic conditions detected pre-symptomatically, simultaneously... -
Analyzing the effects of the choice of model in the context of marginal chang...
Abstract Literature on the choice of model for deriving an input–output table (IOT) from a pair of supply–use tables (SUTs) has focused on the consequences for the IOT and the... -
Associations between the orexin (hypocretin) receptor 2 gene polymorphism Val...
Abstract Background Many genetic and environmental factors are involved in the etiology of nicotine dependence. Although several candidate gene variations have been reported by... -
Associating somatic mutations to clinical outcomes: a pan-cancer study of sur...
Abstract We developed subclone multiplicity allocation and somatic heterogeneity (SMASH), a new statistical method for intra-tumor heterogeneity (ITH) inference. SMASH is... -
The whole - genome expression analysis of peripheral blood mononuclear cells ...
Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the...
