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Male-benefit sexually antagonistic genotypes show elevated vulnerability to i...
Abstract Background There is theoretical and empirical evidence for strong sexual selection in males having positive effects on population viability by serving to purify the... -
Anti-malarial treatment outcomes in Ethiopia: a systematic review and meta-an...
Abstract Background Ethiopia is among countries with a high malaria burden. There are several studies that assessed the efficacy of anti-malarial agents in the country and this... -
Perspectives of policy-makers and stakeholders about health care waste manage...
Abstract Background In South Africa, a new primary health care (PHC) re-engineering initiative aims to scale up the provision of community-based care (CBC). A central element in... -
Identification of a major Listeria monocytogenes outbreak clone linked to sof...
Abstract Background Molecular subtyping and enhanced surveillance in Lombardy region identified a cluster of possibly related listeriosis cases from 2006 to 2010. This cluster... -
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Efficacy, safety and effectiveness of licensed rotavirus vaccines: a systemat...
Abstract Background RotaTeq™ (RV5; Merck & Co. Inc., USA) and Rotarix™ (RV1, GlaxoSmithKline, Belgium) vaccines, developed to prevent rotavirus diarrhea in children under... -
Dissemination and implementation research in dementia care: a systematic scop...
Abstract Background The need to better understand implementing evidence-informed dementia care has been recognised in multiple priority-setting partnerships. The aim of this... -
Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
UK national clinical audit: management of pregnancies in women with HIV
Abstract Background The potential for HIV transmission between a pregnant woman and her unborn child was first recognized in 1982. Since then a complex package of measures to... -
Comparison of anti-malarial drugs efficacy in the treatment of uncomplicated ...
Abstract Background Artemisinin-based combination therapy (ACT) and novel drug combinations are available and used in African countries to treat uncomplicated malaria. Network... -
Pilot study comparing the Childhood Arthritis & Rheumatology Research All...
Abstract Objectives To assess the feasibility of studying the comparative effectiveness of the Childhood Arthritis and Rheumatology Research Alliance (CARRA) consensus treatment... -
The potential role of infectious agents and pelvic inflammatory disease in ov...
Abstract Background The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease... -
A systematic review of complementary feeding practices in South Asian infants...
Abstract Background Sub-optimal nutrition among children remains a problem across South Asia (SA). Appropriate complementary feeding practices (CFP) can greatly reduce this... -
Early morning urine collection to improve urinary lateral flow LAM assay sens...
Abstract Background Urine LAM testing has been approved by the WHO for use in hospitalised patients with advanced immunosuppression. However, sensitivity remains suboptimal. We... -
Estimating the cost-effectiveness of daclatasvir + sofosbuvir versus sofosbuv...
Abstract Background As treatments for chronic hepatitis C are moving away from interferon-containing regimens, the most appropriate allocation of resources to higher cost,... -
Facilitators and barriers of change toward an elder-friendly surgical environ...
Abstract Background Current acute care surgical practices do not focus on the unique needs of older adults. Adverse outcomes in older patients result from a complex... -
Socioeconomic status is associated with symptom severity and sickness absence...
Abstract Background The burden of infectious intestinal disease (IID) in the UK is substantial. Negative consequences including sickness absence are common, but little is known... -
Disease severity determines health-seeking behaviour amongst individuals with...
Abstract Background Seasonal influenza epidemics place considerable strain on health services. Robust systems of surveillance are therefore required to ensure preparedness.... -
Removal of the product from the culture medium strongly enhances free fatty a...
Abstract Background Cyanobacterial mutants engineered for production of free fatty acids (FFAs) secrete the products to the medium and hence are thought to be useful for biofuel... -
Development of a core outcome set for clinical trials in facial aging: study ...
Abstract Background Facial aging is a concern for many patients. Wrinkles, loss of volume, and discoloration are common physical manifestations of aging skin. Genetic heritage,...
