498 items found

Types: other Groups: figshare Tags: 39999 Chemical Sciences not elsewhere classified Medicine Physiology

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    Clinical factors associated with the recovery of cardiovascular autonomic neu...

    Abstract Background Cardiovascular autonomic neuropathy (CAN) is a major cause of morbidity and mortality in diabetes patients. Although several risk factors for CAN progression...
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    Association between pre-pregnancy body weight and dietary pattern with large-...

    Abstract Background Both obesity and gestational diabetes (GDM) are associated with adverse outcomes. Diet during pregnancy impacts weight gain and fetal growth. Therefore, we...
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    Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage exp...

    Abstract Background Sprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD). In vitro...
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    Jejunal villus absorption and paracellular tight junction permeability are ma...

    Abstract Background Food-grade TiO2 (E171 in the EU) is widely used as a coloring agent in foodstuffs, including sweets. Chronic dietary exposure raises concerns for human...
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    Glucagon-like peptide-1 receptor agonists and heart failure in type 2 diabete...

    Abstract Background The effect of glucagon-like peptide-1(GLP-1) receptor agonists on heart failure remains uncertain. We therefore conducted a systematic review to assess the...
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    Public release of hospital quality data for referral practices in Germany: re...

    Abstract Objective To evaluate the impact of different dissemination channels on the awareness and usage of hospital performance reports among referring physicians, as well as...
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    Coronary calcification as a predictor of cardiovascular mortality in advanced...

    Abstract Background Patients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been...
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    Type 2 diabetes and cardiometabolic risk may be associated with increase in D...

    Abstract Background Subclinical hypercortisolism and hypothalamic-pituitary-adrenal (HPA) axis dysfunction are associated with type 2 diabetes (T2DM), cardiovascular disease,...
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    A randomized, double-blind, placebo-controlled crossover clinical trial to ev...

    Abstract Background Allium hookeri is widely consumed as a vegetable and herbal medicine in Asia. A. hookeri has been reported anti-inflammatory, anti-obesity, osteoblastic,...
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    Does growth hormone supplementation improve oocyte competence and IVF outcome...

    Abstract Background Many studies have demonstrated the benefits of the addition of growth hormone (GH) to the controlled ovarian stimulation protocol in vitro fertilization...
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    Plasmonic spectral splitting in multi-resonator-coupled waveguide systems

    Spectral splitting is numerically investigated in a metal-insulator-metal plasmonic waveguide coupled with a series of disk cavities for the first time to our best knowledge....
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    Randomized controlled studies on the efficacy of antiarthritic agents in inhi...

    Abstract Background As an initial step in the development of a local therapeutic to treat osteoarthritis (OA), a number of agents were tested for their ability to block...
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    Prolonged preoperative treatment of acromegaly with Somatostatin analogs may ...

    Abstract Background This study aimed to investigate preoperative somatostatin analogs (SSAs) treatment on the surgical outcome in patients with acromegaly. Methods An analysis...
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    Increased circulating resistin levels in early-onset breast cancer patients o...

    Abstract Background Early-onset breast cancer (EOBC) affects about one in 300 women aged 40 years or younger and is associated with worse outcomes than later onset breast...
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    Diet-related greenhouse gas emissions assessed by a food frequency questionna...

    Abstract Background The current food system generates about 25 % of total greenhouse gas emissions (GHGE), including deforestation, and thereby substantially contributes to the...
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    Leptin receptor signaling is required for high-fat diet-induced atrophic gast...

    Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated...
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    Developmental basis for intestinal barrier against the toxicity of graphene o...

    Abstract Background Intestinal barrier is crucial for animals against translocation of engineered nanomaterials (ENMs) into secondary targeted organs. However, the molecular...
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    Base excess and hematocrit predict response to indomethacin in very low birth...

    Abstract Background The treatment of patent ductus arteriosus (PDA) in very low birth weight (VLBW) infants remains a challenge. The ability to predict which infants will...