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Waist circumference is associated with major adverse cardiovascular events in...
Abstract Background Although studies have shown that waist circumference (WC) is positively associated with an increased risk of cardiovascular diseases among the normal... -
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming gro...
Abstract Background Pirfenidone, an antifibrotic agent used for the treatment of idiopathic pulmonary fibrosis (IPF), functions by inhibiting myofibroblast differentiation,... -
The Red Queen in the Repository: metadata quality in an ever-changing environ...
This fileset contains a preprint version of the conference paper (.pdf), presentation slides (as .pptx) and the dataset(s) and validation schema(s) for the IDCC 2019 (Melbourne)... -
Leptin receptor signaling is required for high-fat diet-induced atrophic gast...
Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated... -
Additional file 2 of Metabolic characterization of aggressive breast cancer c...
Additional file 2: Supplemental Figure 2. Mitochondrial membrane potential of SUM149 invading cells. -
Additional file 1 of Impact of malnutrition on systemic immune and metabolic ...
Additional file 1: Figure S1. Flowchart for the study participant recruitment. A flowchart illustrating participant recruitment to the study. -
Increased circulating microRNA-122 is associated with mortality and acute liv...
Abstract Background Acute liver injury in patients with ARDS decreases survival but early stages may be easily missed due to the lack of sufficient biomarkers signalling its... -
The human fetal adrenal produces cortisol but no detectable aldosterone throu...
Abstract Background Human fetal adrenal glands are highly active and, with the placenta, regulate circulating progesterone, estrogen and corticosteroids in the fetus. At birth... -
Circulating microRNA-92a level predicts acute coronary syndrome in diabetic p...
Abstract Purpose This study was designed to explore the value of monitoring miR-92a in T2DM patients with coronary heart disease (CHD). Materials and methods 40 ACS patients... -
Single nucleotide polymorphisms in apoptosis pathway are associated with resp...
Abstract Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis... -
Prevalence and profile of adverse drug reactions in high-risk pregnancy: a co...
Abstract Background Commonly used drugs in pregnant women include antihypertensives, hypoglycemic agents, analgesics, antimicrobials, antiemetics and antispasmodics but the use... -
Additional file 3: Figure S3. of Thrombin-induced, TNFR-dependent miR-181c do...
Schematic overview of thrombin’s effects upon miR-181c and MLL1 in human microglia. Thrombin (via PAR4) induces TNF-α secretion from human microglia [21]. Thrombin-induced TNF-α... -
Canine ovarian gonadoblastoma with dysgerminoma overgrowth: a case study and ...
Abstract Background Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients... -
MOESM2 of Paclitaxel-activated astrocytes produce mechanical allodynia in mic...
Additional file 2: Figure S2. Cytokine array indicates potential regulation of chemokines in astrocytes after paclitaxel exposure. A, Illustration of the cytokine array with 40... -
Additional file 1: of Umbilical cord as a long-term source of activatable mes...
Figure S1. Antibody staining of early and late induced MSC-EMs. Early and late induced MSC-EMs were stained with antibodies for CD73, CD90, and CD105 to confirm the mesenchymal... -
Additional file 8: of Glucocorticoids promote transition of ductal carcinoma ...
Figure S5. Representative immunofluorescence images of human samples of DCIS (6 patients) and DCIS + IDC (6 patients).a Double immunofluorescence of p63 (myoepithelial cells)... -
Proteomic characterization of bovine granulosa cells in dominant and subordin...
Abstract Background Characterization of molecular factors regulating ovarian follicular development is critical to understanding its functional mechanism of controlling the... -
Terlipressin for the treatment of hepatorenal syndrome: An overview of curren...
Hepatorenal syndrome (HRS) is a serious complication of liver cirrhosis, which is of pre-renal origin due to central volume depletion together with cardiac dysfunction and... -
Oligo-carrageenan kappa increases glucose, trehalose and TOR-P and subsequent...
Abstract Background It has been previously shown that oligo-carrageenan (OC) kappa increases growth, photosynthesis and activities of enzymes involved in basal and secondary... -
RETRACTED ARTICLE: Neferine hinders choriocarcinoma cell proliferation, migra...
The comprehensive pathological peculiarities of Neferine (NEF) have been testified in disparate diseases. But, the functions of NEF in choriocarcinoma progression remain...
