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Exploring why global health needs are unmet by research efforts: the potentia...
Abstract Background It has been well established that research is not addressing health needs in a balanced way — much more research is conducted on diseases with more burden in... -
The effect of regularly dosed paracetamol versus no paracetamol on renal func...
Abstract Background Plasmodium knowlesi is the most common cause of human malaria in Malaysia. Acute kidney injury (AKI) is a frequent complication. AKI of any cause can have... -
Comparison of efficacy and safety of drug-eluting versus uncoated balloon ang...
Abstract Background This quantitative meta-analysis was conducted to evaluate the efficacy and safety of drug-eluting balloon (DEB) vs. uncoated balloon (UCB) in patients with... -
Risk factors influencing survival of acellular porcine corneal stroma in infe...
Abstract Background A worldwide lack of donor corneas demands the bioengineered corneas be developed as an alternative. The primary objective of the current study was to... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Quantitative analysis of a rare disease network’s international contact datab...
Abstract Background Castleman disease (CD) describes a group of rare and poorly understood lymphoproliferative disorders that include unicentric CD (UCD), Human Herpes Virus-8... -
Clinical characteristics of the patients with bacteremia due to Moraxella cat...
Abstract Background Invasive diseases due to Moraxella catarrhalis are rare in children, even in immunocompromised hosts. Therefore, data regarding clinical characteristics and... -
Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interact...
Abstract Background Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However,... -
Distinct core promoter codes drive transcription initiation at key developmen...
Abstract Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key... -
The association of urinary sodium excretion and the need for renal replacemen...
Abstract Background Restriction of dietary sodium is routinely recommended for patients with chronic kidney disease (CKD). Whether or not sodium intake is associated with the... -
The human disease network in terms of dysfunctional regulatory mechanisms
Abstract Background Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug... -
Association of functional and structural social support with chronic kidney d...
Abstract Background There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of... -
Induction of the immunoprotective coat of Yersinia pestis at body temperature...
Abstract Background Thermal regulation of gene expression occurs in many microorganisms, and is mediated via several typical mechanisms. Yersinia pestis is the causative agent... -
Food systems transformations, ultra-processed food markets and the nutrition ...
Abstract Background Attracted by their high economic growth rates, young and growing populations, and increasingly open markets, transnational food and beverage corporations... -
Association between probiotic and yogurt consumption and kidney disease: insi...
Abstract Background Data from experimental animals suggest that probiotic supplements may retard CKD progression. However, the relationship between probiotic use, frequent... -
Inhibition of Salmonella Typhimurium adhesion, invasion, and intracellular su...
Abstract Salmonella enterica serovar Typhimurium infects intestinal epithelia and macrophages, which is prevented by inhibiting adhesion and cell invasion. This study aimed to... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Urinary proteomics for prediction of mortality in patients with type 2 diabet...
Abstract Background The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of... -
DNetDB: The human disease network database based on dysfunctional regulation ...
Abstract Disease similarity study provides new insights into disease taxonomy, pathogenesis, which plays a guiding role in diagnosis and treatment. The early studies were... -
Annual Dialysis Data Report 2015, JSDT Renal Data Registry
Abstracts ᅟ The annual survey of Japanese Society for Dialysis Therapy Renal Data Registry (JRDR) was conducted for 4380 dialysis facilities at the end of 2015, among which 4321...
