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Comparison of efficacy and safety of drug-eluting versus uncoated balloon ang...
Abstract Background This quantitative meta-analysis was conducted to evaluate the efficacy and safety of drug-eluting balloon (DEB) vs. uncoated balloon (UCB) in patients with... -
Plasma matrix metalloproteinases are associated with incident cardiovascular ...
Abstract Background Altered regulation of extracellular matrix remodeling by matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinase (TIMP) may contribute to... -
Clinical characteristics of the patients with bacteremia due to Moraxella cat...
Abstract Background Invasive diseases due to Moraxella catarrhalis are rare in children, even in immunocompromised hosts. Therefore, data regarding clinical characteristics and... -
Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interact...
Abstract Background Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However,... -
Distinct core promoter codes drive transcription initiation at key developmen...
Abstract Background Development is largely driven by transitions between transcriptional programs. The initiation of transcription at appropriate sites in the genome is a key... -
The association of urinary sodium excretion and the need for renal replacemen...
Abstract Background Restriction of dietary sodium is routinely recommended for patients with chronic kidney disease (CKD). Whether or not sodium intake is associated with the... -
The human disease network in terms of dysfunctional regulatory mechanisms
Abstract Background Elucidation of human disease similarities has emerged as an active research area, which is highly relevant to etiology, disease classification, and drug... -
Association of functional and structural social support with chronic kidney d...
Abstract Background There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of... -
Food systems transformations, ultra-processed food markets and the nutrition ...
Abstract Background Attracted by their high economic growth rates, young and growing populations, and increasingly open markets, transnational food and beverage corporations... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Urinary proteomics for prediction of mortality in patients with type 2 diabet...
Abstract Background The urinary proteomic classifier CKD273 has shown promise for prediction of progressive diabetic nephropathy (DN). Whether it is also a determinant of... -
DNetDB: The human disease network database based on dysfunctional regulation ...
Abstract Disease similarity study provides new insights into disease taxonomy, pathogenesis, which plays a guiding role in diagnosis and treatment. The early studies were... -
Challenges in the construction of knowledge bases for human microbiome-diseas...
Abstract The last few years have seen tremendous growth in human microbiome research, with a particular focus on the links to both mental and physical health and disease.... -
Caring for older patients with advanced chronic kidney disease and considerin...
Abstract Background Older patients with advanced chronic kidney disease often do not understand treatment options for renal replacement therapy, conservative kidney management,... -
The French National Registry of patients with Facioscapulohumeral muscular dy...
Abstract Background Facioscapulohumeral muscular dystrophy is a rare inherited neuromuscular disease with an estimated prevalence of 1/20,000 and France therefore harbors about... -
Self-monitoring of health data by patients with a chronic disease: does disea...
Background: There is a growing emphasis on self-monitoring applications that allow patients to measure their own physical health parameters. A prerequisite for achieving... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Point-of-care ultrasound curriculum for internal medicine residents: what do ...
Abstract Background Point-of-care Ultrasound is a relative new diagnostic tool for internists. Since 2019, it is a mandatory skill for internal medicine residents in the... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
The healthcare costs of treating human papillomavirus-related cancers in Norway
Abstract Background Public health efforts to prevent human papillomavirus (HPV)-related cancers include HPV vaccination and cervical cancer screening. We quantified the annual...
