496 items found

Types: publication Tags: Biochemistry Biotechnology Cancer Pharmacology

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  • publication

    Synthesis and biological evaluation of pyrrolidine-based T-type calcium chann...

    The treatment of neuropathic pain is one of the urgent unmet medical needs and T-type calcium channels are promising therapeutic targets for neuropathic pain. Several potent...
  • publication

    Additional file 1 of Overlap between adverse events (AEs) and serious adverse...

    Additional file 1: Supplementary Table 1. Free Text Categorisations. Supplementary Table 2. ICON8 Adverse Events Mapped to Serious Adverse Events. Supplementary Table 3. ICON8...
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    Characterisation of aroma profiles of commercial sufus by odour activity valu...

    Sufu is a solid-state fermented product made from soya beans. For the sake of quality control and regulation purposes, it is essential to be able to identify key odorants of...
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    r37980778c78--3a632bf31424babcdf49a8c68576710b

    A variety of semisynthetic derivatives of natural antibacterial glycopeptide antibiotics such as vancomycin, eremomycin, ristocetin A, teicoplanin A2-2, DA-40926, their...
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    Adherence to standard-dose or low-dose statin treatment and low-density lipop...

    Objective:To determine the association between adherence, dose and low-density lipoprotein (LDL) cholesterol response in patients with type 2 diabetes initiating statin...
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    Palladium-Catalyzed Stereoselective Hydrogenolysis of Conjugated 1,1-Dibromo-...

    Palladium-Catalyzed Stereoselective Hydrogenolysis of Conjugated 1,1-Dibromo-1-alkenes to (Z)-1-Bromo-1-alkenes. An Application to Stepwise and One-Pot Synthesis of Enediynes...
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    Preparation, Structure, and Ethylene Polymerization Behavior of Bis(imino)pyr...

    The synthesis, characterization, and ethylene polymerization behavior of a family of chromium(III) complexes of formula [2,6-bis(imino)pyridyl]CrCl3 is reported. The X-ray...
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    Scandium-Catalyzed Copolymerization of Ethylene with Dicyclopentadiene and Te...

    Scandium-Catalyzed Copolymerization of Ethylene with Dicyclopentadiene and Terpolymerization of Ethylene, Dicyclopentadiene, and Styrene
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    dedup_wf_001--8ad2ed0b97141597ef69887e5bf4caf7

    Resazurin reduction by J774A.1 (A) and A549 (B) cells exposed to particles. Average fold-effect (FE) over control ± standard error values are shown (n = 5). ATP content of...
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    dedup_wf_001--cedafc998d1fc5debcd248d1a74f7628

    Figure S1. Schematic of drug-inducible sgRNA expression lentiviral vectors. Figure S2. Nucleotide sequence presentation of the DOX- and IPTG-inducible U6 promoter variants used...
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    r37980778c78--3c1d9ac117fe9934375e9d060e208168

    Strong base anion-exchange resins represent an important option for water utilities and homeowners to address growing concerns with nitrate, arsenate, and perchlorate...
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    Leading scientists towards openness

    Some questions, ideas and prompts for our session at science online 2013
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    r37980778c78--ee30ab74a223500e10d3c1187e92be7a

    The formation of silica- and titania-coated single-wall carbon nanotubes (SWNTs) using a mutlifunctional peptide to both suspend SWNTs and direct the precipitation of silica and...
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    Click Pre-Targeted Pet Imaging Of Antibodies Using Novel Trans-Cyclooctene De...

    Monoclonal antibodies (mAbs), as vectors for delivering therapeutics or imaging agents, represent one of the most rapidly expanding tools in targeted therapy. Tracking mAbs and...
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    Reducing Motor Vehicle Greenhouse Gas Emissions in a Non-California State: A ...

    Approaches for reducing greenhouse gas (GHG) emissions from motor vehicles include more-efficient vehicles, lower-carbon fuels, and reducing vehicle-kilometers traveled (VKT)....
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    Proposed reference dose for toxaphene carcinogenicity based on constitutive a...

    Toxaphene is a liver tumor promoter in B6C3F1 mice but not in F344 rats or hamsters. Recent studies demonstrate that key events leading to the mouse liver tumor response for...
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    A Ureido-Thioisobutyric Acid (GW9578) Is a Subtype-Selective PPARα Agonist wi...

    A Ureido-Thioisobutyric Acid (GW9578) Is a Subtype-Selective PPARα Agonist with Potent Lipid-Lowering Activity
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    Optimization of the extraction of bioactive molecules from <i>Lycium barbarum...

    Novel food, super food, wolfberry, the Himalayan longevity fruit. Several different and, even more, colourful names define the fruits of Lycium barbarum L., one of the most...
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    r37980778c78--59fdf7dd0ae1d6f8f4fbfbd1c5bea8e0

    Electrosynthesis of a Low Band Gap π-Conjugated Polymer from a Multibridged Dithienylethylene