-
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Transcriptomic data from two primary cell models stimulating human monocytes ...
Abstract Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used... -
BRACAVENIR: an observational study of expectations and coping in young women ...
Abstract Background In families with high risk of hereditary breast/ovarian cancer (HBOC), women before age 30 do not yet undergo clinical screening, but they are exposed to... -
Immediate effects of a lumbar spine manipulation on pain sensitivity and post...
Abstract Background According to the American Physical Therapy Association, there is strong evidence to show that vertebral mobilization and manipulation procedures can be used... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
Chronic wide-field imaging of brain hemodynamics in behaving animals
Chronically monitoring cerebral activities in awake and freely moving status is very important in physiological and pathological studies. We present a novel standalone... -
Use of a decision aid did not decrease decisional conflict in patients with c...
Abstract Background Although a model for shared decision-making is important for patient-centered care, decisional conflict can emerge when patients participate in the... -
Could low birth weight and preterm birth be associated with significant burde...
Abstract Background Approaches for the prevention and treatment of hip osteoarthritis (OA) remain limited. There are recent data suggesting that low birth weight (LBW) and... -
Impact of hemoperfusion with polymyxin B added to hemofiltration in patients ...
Abstract Background Septic shock is a leading cause of death in critical patients. In patients with gram-negative septic shock, hemoperfusion with polymyxin B aims to remove... -
Crying spells triggered by thumb-index rubbing after thalamic stroke: a case ...
Abstract Background Pathologic crying, devoid of any emotional counterpart, is known to occur as a consequence of various brain stem, cortical hemispheric and cerebellar lesions... -
Oxidative stress enhances the expression of IL-33 in human airway epithelial ...
Abstract Background Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, and its possible involvement in the pathophysiology of COPD and viral-induced... -
Sublingual microcirculation does not reflect red blood cell transfusion thres...
Abstract Purpose Hemoglobin (Hb) transfusion thresholds are established in intensive care units. A restrictive transfusion threshold (Hb 70–75 g/l) is recommended in septic... -
Tonic ATP-mediated growth suppression in peripheral nerve glia requires arres...
Abstract Normal Schwann cells (SCs) are quiescent in adult nerves, when ATP is released from the nerve in an activity dependent manner. We find that suppressing nerve activity... -
Influence of menstrual cycle phase on resting-state functional connectivity i...
Abstract Background Sex differences in tobacco-related morbidity and mortality exist, with women experiencing more severe health consequences and greater difficulty with smoking... -
MyD88-dependent pro-interleukin-1β induction in dendritic cells exposed to fo...
Abstract Background Dendritic cells (DCs) are specialized first-line sensors of foreign materials invading the organism. These sentinel cells rely on pattern recognition... -
Comparability of three intraocular pressure measurement: iCare pro rebound, n...
Abstract Background Measurement of intraocular pressure (IOP) is essential for glaucoma patients. Many factors such as central corneal thickness (CCT) can affect the accuracy of... -
Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage...
Abstract Background Intracerebral hemorrhage (ICH) is a devastating medical emergency with high mortality and severe neurological deficit. ICH-related poor outcomes are due to a... -
Computed tomography-derived area and density of pectoralis muscle associated ...
Abstract Background Muscle wasting is associated with prognosis in patients with chronic obstructive pulmonary disease (COPD). The cross-sectional area of skeletal muscles on... -
Effects of methylprednisolone on blood-brain barrier and cerebral inflammatio...
Abstract Background Cognitive dysfunction is a frequent complication to open-heart surgery. Cerebral inflammation caused by blood-brain barrier (BBB) dysfunction due to a... -
The potassium channel KCa3.1 constitutes a pharmacological target for astrogl...
Abstract Background Reactive astrogliosis is one of the significantly pathological features in ischemic stroke accompanied with changes in gene expression, morphology, and...
