-
Comparing diagnostic and prognostic performance of two-gene promoter methylat...
Abstract Background Prostate cancer (PCa) is one of the most common cancers among men worldwide. Current screening methods for PCa display limited sensitivity and specificity,... -
Cell-based reference samples designed with specific differences in microRNA b...
Abstract Background We demonstrate the feasibility of creating a pair of reference samples to be used as surrogates for clinical samples measured in either a research or... -
Timing of repair and mesh use in traumatic abdominal wall defects: a systemat...
Abstract Background Traumatic abdominal wall hernias or defects (TAWDs) after blunt trauma are rare and comprehensive literature on this topic is scarce. Altogether, there is no... -
A kinetic metabolic study of lipid production in Chlorella protothecoides und...
Abstract Background Microalgae have been proposed as potential platform to produce lipid-derived products, such as biofuels. Knowledge on the intracellular carbon flow... -
MiR-182 promotes cancer invasion by linking RET oncogene activated NF-κB to l...
Abstract Background Dominant-activating mutations in the RET proto-oncogene, a receptor tyrosine kinase, are responsible for the development of medullary thyroid carcinoma (MTC)... -
The active role of the transcription factor Sp1 in NFATc2-mediated gene regul...
Abstract Background Adenocarcinoma of the pancreas is one of the most aggressive tumor diseases affecting the human body. The oncogenic potential of pancreatic cancer is mainly... -
Copeptin levels and commonly used laboratory parameters in hospitalised patie...
Abstract Background Hypernatraemia is common in inpatients and is associated with substantial morbidity. Its differential diagnosis is challenging, and delayed treatment may... -
Combination chemotherapy with 5-fluorouracil and dacarbazine in advanced medu...
Combination chemotherapy with 5-fluorouracil and dacarbazine in advanced medullary thyroid cancer, a possible alternative? -
Serum miRNAs, a potential prognosis marker of loco-regionally advanced nasoph...
Abstract Background Serum miRNA was once found as potential disease survival index,thus we investigated the role of miRNA in predicting prognosis in loco-regionally advanced NPC... -
Single-cell ATAC-seq signal extraction and enhancement with SCATE
Abstract Single-cell sequencing assay for transposase-accessible chromatin (scATAC-seq) is the state-of-the-art technology for analyzing genome-wide regulatory landscapes in... -
A self-marker-like protein governs hemocyte allorecognition in Halocynthia ro...
Abstract Background Self-incompatibility, fusion/non-fusion reactions, and contact reactions (CRs) have all been identified as allorecognition phenomena in ascidians. CR is a... -
Operational utility of the reverse-transcription recombinase polymerase ampli...
Abstract Background A method for rapid detection of dengue virus using the reverse-transcription recombinase polymerase amplification (RT-RPA) was recently developed, evaluated... -
Archaic mitochondrial DNA inserts in modern day nuclear genomes
Abstract Background Traces of interbreeding of Neanderthals and Denisovans with modern humans in the form of archaic DNA have been detected in the genomes of present-day human...
