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Prevalence and serotype distribution of nasopharyngeal carriage of Streptococ...
Abstract Background To explore the overall prevalence and serotype distribution of nasopharyngeal carriage of Streptococcus pneumoniae(S. pneumoniae) among healthy children.... -
Effects of cyanobacterial toxins on the human gastrointestinal tract and the ...
Abstract Background Cyanobacterial blooms occur with increasing frequency in freshwater ecosystems, posing a hazard to human and environmental health. Exposure of human to... -
Cortical vein thrombosis in adult patients of cerebral venous sinus thrombosi...
Abstract Background Cortical vein thrombosis (CVT) receives little attention in adult patients with cerebral venous sinus thrombosis (CVST). This study aimed to investigate the... -
The potential role of infectious agents and pelvic inflammatory disease in ov...
Abstract Background The etiological cause of ovarian cancer is poorly understood. It has been theorized that bacterial or viral infection as well as pelvic inflammatory disease... -
Development of gut inflammation in mice colonized with mucosa-associated bact...
Abstract Background Disturbances in the intestinal microbial community (i.e. dysbiosis) or presence of the microbes with deleterious effects on colonic mucosa has been linked to... -
Prevalence of nasal colonization by methicillin-resistant Staphylococcus aure...
Abstract Objective The purpose of this study is to investigate the prevalence of MRSA among people living with HIV/AIDS (PLHA) being monitored in a tertiary outpatient hospital... -
Unique patterns of lower respiratory tract microbiota are associated with inf...
Abstract Background The lung microbiome maintains the homeostasis of the immune system within the lungs. In acute respiratory distress syndrome (ARDS), the lung microbiome is... -
The whole - genome expression analysis of peripheral blood mononuclear cells ...
Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the... -
Systematic review of time trends in the prevalence of Helicobacter pylori inf...
Abstract It has been suggested that the prevalence of Helicobacter pylori infection has stabilized in the USA and is decreasing in China. We conducted a systematic literature... -
A systematic review of the association between delayed appropriate therapy an...
Abstract Background Temporal relationships between the time to appropriate antibiotic therapy and outcomes are not well described. Methods A systematic literature review and... -
Anthroponotic transmission of Cryptosporidium parvum predominates in countrie...
Abstract Background Globally cryptosporidiosis is one of the commonest causes of mortality in children under 24 months old and may be associated with important longterm health... -
Production results from piglets vaccinated in a field study in Spain with a T...
Abstract Background PRRS is a viral disease of pigs and sows that is one of the most costly to the pig industry worldwide. The disease can be controlled by focusing on different... -
SOX2 interferes with the function of CDX2 in bile acid-induced gastric intest...
Abstract Background Intestinal metaplasia (IM) is a premalignant lesion associated with gastric cancer. Both animal and clinical studies have revealed that bile acid reflux and... -
Burden of pneumocystis pneumonia in HIV-infected adults in sub-Saharan Africa...
Abstract Background Seroprevalence data and clinical studies in children suggest that the burden of pneumocystis pneumonia (PCP) in Africa may be underestimated. We performed a... -
Design, synthesis and biological activity of hydroxybenzoic acid ester conjug...
Abstract We prepared 16 novel hydroxybenzoic acid ester conjugates of phenazine-1-carboxylic acid (PCA) and investigated their biological activity. Most of the synthesized... -
Divergent transcriptomic responses underlying the ranaviruses-amphibian inter...
Abstract Background Ranaviruses (family Iridoviridae, nucleocytoplasmic large DNA viruses) have been reported as promiscuous pathogens of cold-blooded vertebrates. Rana grylio... -
Pathway activity profiling of growth factor receptor network and stemness pat...
Abstract Background Gene expression profiling of rare cancers has proven challenging due to limited access to patient materials and requirement of intact, non-degraded RNA for... -
Major differential gene regulation in Coxiella burnetii between in vivo and i...
Abstract Background Coxiella burnetii is the causative agent of the zoonotic disease Q fever. As it is an intracellular pathogen, infection by C. burnetii requires adaptation to... -
Benefits of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI)...
Abstract Background The Phase III PINNACLE studies assessed the efficacy and safety of glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI), a dual long-acting... -
Genome-wide characterization of human L1 antisense promoter-driven transcripts
Abstract Background Long INterspersed Element-1 (LINE-1 or L1) is the only autonomously active, transposable element in the human genome. L1 sequences comprise approximately 17...