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The Linkage of Catalysis and Regulation in Enzyme Action. Fluoropyruvate as a...
Pyruvate decarboxylase, a thiamin-diphosphate (ThDP) dependent enzyme from the yeast Saccharomyces cerevisiae (SCPDC), catalyzes the conversion of fluoropyruvate to carbon... -
Highly Luminescent, Triple- and Quadruple-Stranded, Dinuclear Eu, Nd, and Sm(...
The bis(β-diketone) ligands 1,3-bis(3-phenyl-3-oxopropanoyl)benzene, H2L1 and 1,3-bis(3-phenyl-3-oxopropanoyl) 5-ethoxy-benzene, H2L2, have been prepared for the examination of... -
Technical Challenges Involved in Implementation of VOC Reactivity-Based Contr...
Controlling VOC emissions on the basis of their individual contribution to ozone formation has been subject to extensive discussion and research in past years, and the concept... -
Dendrimer-Supported Oligothiophene Synthesis: Aliphatic Ether Dendrimers in ...
The first dendrimer-supported synthesis of oligothiophenes is reported. The dendrimer serves both as a solubilizing group and a “handle” to facilitate the iterative synthesis of... -
Predicting Bioavailability of Sediment-Associated Organic Contaminants for <i...
Biota-sediment accumulation factors (BSAF) were calculated for Diporeia spp. and oligochaete worms exposed to polychlorinated biphenyls (PCBs) and polycyclic aromatic... -
CAUTION: Popular "Benchmark" Data Sets Do Not Distinguish the Merits of 3D QS...
The quality of 3D QSAR models obtained using extremely simple descriptors was examined for nine popular data sets, including the well-known set of 31 steroids, which for 20... -
Total Synthesis of the Ristocetin Aglycon
The first total synthesis of the ristocetin aglycon is described employing a modular and highly convergent strategy. An effective 12-step (12% overall) synthesis of the ABCD... -
Discovery of and Mechanistic Insight into a Ligand-Modulated Palladium-Cataly...
We describe the discovery of a new N-heterocyclic carbene-modulated Pd catalyst for the Wacker oxidation that does not require molecular oxygen but instead uses TBHP as a... -
Sugar-containing Polyamines Prepared Using Galactose Oxidase Coupled with Che...
Sugar-containing Polyamines Prepared Using Galactose Oxidase Coupled with Chemical Reduction -
A New Highly Asymmetric Chelation-Controlled Heck Arylation
This communication describes the development of a new highly asymmetric chelation-controlled Heck arylation. The methodology permits formation of 2-aryl-2-methyl cyclopentanones... -
Carbon Dioxide Sequestration in Cement Kiln Dust through Mineral Carbonation
Carbon sequestration through the formation of carbonates is a potential means to reduce CO2 emissions. Alkaline industrial solid wastes typically have high mass fractions of... -
Development of Chiral Nucleophilic Pyridine Catalysts: Applications in Asymm...
TADMAP (1a), a new chiral DMAP catalyst, has been designed to place a C(3)-benzylic trityl group over one face of the pyridine ring, while a C(3)-benzylic acetoxy group creates... -
Highly selective cobalt-catalyzed hydrovinylation of styrene
: The hydrovinylation reaction is a codimerization of a 1,3-diene or vinyl arene and ethene with great potential for fine chemicals and pharmaceuticals. For the first time,... -
Multiplexed Sandwich Immunoassays using Electrochemiluminescence Imaging Reso...
A new class of bead-based microarray that uses electrogenerated chemiluminescence (ECL) as a readout mechanism to detect multiple antigens simultaneously is presented. This... -
Atomic Layer Deposition of Metal Tellurides and Selenides Using Alkylsilyl Co...
Atomic layer deposition (ALD) of metal selenide and telluride thin films has been limited because of a lack of precursors that would at the same time be safe and exhibit high... -
Total Synthesis of Archazolid A.
The archazolids are complex polyketides isolated from the myxobacterium Archangium gephyra and are potent inhibitors of vacuolar type ATPases. Herein, we report the first total... -
Life-cycle assessment of biodiesel production from microalgae
International audience; This paper provides an analysis of the potential environmental impacts of biodiesel production from microalgae. High production yields of microalgae have... -
Synthesis of (+)-Complanadine A, an Inducer of Neurotrophic Factor Excretion
A total synthesis of the Lycopodium alkaloid (+)-complanadine A is described. Complanadine A has been shown to induce the secretion of neurotrophic factors from 1321N1 cells,... -
Efficient Removal of Estrogenic Activity during Oxidative Treatment of Waters...
The discharge of synthetic and natural steroid estrogens from municipal wastewaters to the aquatic environment has received increased attention because of their potential... -
Phase-Vanishing Reactions that Use Fluorous Media as a Phase Screen. Facile, ...
In fluorous triphasic reactions, such as bromination of alkenes by dibromine and dealkylation of aromatic ethers by boron tribromide, the middle fluorous phase acts as a liquid...
