-
Pancreatic cancer-initiating cell exosome message transfer into noncancer-ini...
Abstract Background Cancer-initiating cell (CIC) exosomes (CIC-TEX) are suggested reprogramming Non-CIC. Mode of message transfer and engagement of CIC-markers being disputed,... -
Redefining chemotherapy-induced peripheral neuropathy through symptom cluster...
Abstract Background Chemotherapy-induced peripheral neuropathy (CIPN) is common among cancer patients treated with neurotoxic chemotherapy agents. Better knowledge on symptom... -
Sex-specific IL-6-associated signaling activation in ozone-induced lung infla...
Abstract Background Acute ozone (O3) exposure has known deleterious effects on the respiratory system and has been linked with respiratory disease and infection. Inflammatory... -
A metagenome-wide association study of gut microbiota in asthma in UK adults
Abstract Background Asthma, one of the most common chronic respiratory disorders, is associated with the hyper-activation of the T-cell subset of adaptive immunity. The gut... -
Hedgehog signalling does not stimulate cartilage catabolism and is inhibited ...
Abstract Background In osteoarthritis, chondrocytes adopt an abnormal hypertrophic morphology and upregulate the expression of the extracellular matrix-degrading enzymes, MMP-13... -
A meta-analysis of potential biomarkers associated with severity of coronavir...
Abstract Background Prognostic factors for the Coronavirus disease 2019 (COVID1–9) are not well established. This study aimed to summarize the available data on the association... -
Investigation of the host transcriptional response to intracellular bacterial...
Abstract Background During infection by intracellular pathogens, a highly complex interplay occurs between the infected cell trying to degrade the invader and the pathogen which... -
Purification and partial characterization of LdtP, a cell envelope modifying ...
Abstract Background The aggressive spread of Liberibacter asiaticus, a bacterium closely associated with citrus greening, has given rise to an acute crisis in the citrus... -
Lipopolysaccharide-induced neuroinflammation induces presynaptic disruption t...
Abstract Background Systemic inflammation has been linked to synapse loss and cognitive decline in human patients and animal models. A role for microglial release of... -
Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Seroepidemiology and associated risk factors of Toxoplasma gondii in sheep an...
Abstract Background T.gondii is a global zoonotic disease and is considered as the most neglected tropical disease in sub-Saharan countries. The exact seroepidemiological... -
Confident gene activity prediction based on single histone modification H2BK5...
Abstract Background The histones in the core of nucleosomes may be subject to covalent post-transcriptional modifications. These modifications are thought to correlate with and... -
Antibiotic-resistant Escherichia coli from retail poultry meat with different...
Abstract Background We sought to determine if the prevalence of antibiotic-resistant Escherichia coli differed across retail poultry products and among major production... -
Clinical and subclinical endometritis induced alterations in bovine endometri...
Abstract Background Clinical and subclinical endometritis are known to affect the fertility of dairy cows by inducing uterine inflammation. We hypothesized that clinical or... -
A Synthesis of Hepatitis C prevalence estimates in Sub-Saharan Africa: 2000–2013
Abstract Background Hepatitis C (HCV) is a deleterious virus that can be cured with new, highly effective anti-viral treatments, yet more than 185 million individuals worldwide... -
RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung inju...
Abstract Background NLRP3 inflammasome is involved in the inflammatory responses during acute lung injury (ALI). RIP3 triggered NLRP3 inflammasome activation independent of... -
Distinct immune responses of juvenile and adult oysters (Crassostrea gigas) t...
Abstract Since 2008, massive mortality events of Pacific oysters (Crassostrea gigas) have been reported worldwide and these disease events are often associated with Ostreid... -
Multi-drug resistance and extended spectrum beta lactamase producing Gram neg...
Abstract Objective Multidrug resistance (MDR) and extended spectrum beta lactamase (ESBL) producer Gram negative bacteria are considered as a major health problem, globally.... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Contribution of spinal cord glial cells to L. amazonensis experimental infect...
Abstract Background The cellular and molecular pathophysiological mecha\nisms of pain processing in neglected parasitic infections such as leishmaniasis remain unknown. The...
