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r37980778c78--a53b45f678a186371e2191f6aa1b0375
Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a... -
Development of a Novel Self-Microemulsifying Drug Delivery System for Reducin...
The development of HIV protease inhibitors (PIs) has been one of the most significant advances of the past decade in controlling HIV infection. Unfortunately, the benefits of... -
dedup_wf_001--4edd6b37544e4fc6acb3bb4fce0088b7
A major bottleneck for the exploitation of data from the Kepler mission for stellar astrophysics and exoplanet research has been the lack of precise radii and evolutionary... -
Lewis Acid-Promoted Conjugate Addition of Dienol Silyl Ethers to Nitroalkenes...
A novel γ-selective conjugate addition of 1-silyl-substituted dienol ethers to nitroalkenes activated by Lewis acids has been developed. The resulting α,β-unsaturated... -
Additional file 2: Figure S1. of Aberrant KDM5B expression promotes aggressiv...
Relative expression of KDM5B, MALAT1, SNAIL, Vimentin and miR 448 normalized against GAPDH in MCF10A WT, MCF10A OE, MDA-MB-231 WT and MDA-MB-231 KD cells. Data are... -
Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...
A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and... -
In vitro and In vivo Optical Imaging Using Water-Dispersible, Noncytotoxic, L...
A facile method for synthesis of monodisperse, biocompatible, silica coated CdSe/CdS/ZnS quantum rods (QRs) and their use as probes for in vitro and in vivo optical bioimaging... -
Anhydrolide Macrolides. 1. Synthesis and Antibacterial Activity of 2,3-Anhydr...
A series of 3-descladinosyl-2,3-anhydro-6-O-methylerythromycin A 11,12-carbamate analogues have been synthesized and evaluated for antibacterial activity. These compounds were... -
r37980778c78--954d101d912830db6c8952094f5009ff
Fluorescein Redirects a Ruthenium−Octaarginine Conjugate to the Nucleus -
Capsaicin induces cytotoxicity in human osteosarcoma MG63 cells through TRPV1...
An accumulating body of evidence has shown that capsaicin induces apoptosis in various tumor cells as a mechanism of its anti-tumor activity. However, the effects of capsaicin... -
Integrated Comparison of Drug-Related and Drug-Induced Ultra Performance Liqu...
The biochemical variations induced in human primary hepatocyte cultures by reference activators of xenoreceptor CAR (NR1I3) and PXR (NR1I2), i.e., rifampicin, phenobarbital, and... -
Additional file 1: of Measuring implementation in global mental health: valid...
Adult Qualitative_free list. Qualitative guide used for free listing activity. (DOC 46 kb) -
r37980778c78--171b2989a7b99d872f8aab415bba7cb6
A new and promising group of antibacterial agents, collectively known as the oxazolidinones and exemplified by linezolid (PNU-100766, marketed as Zyvox), have recently emerged... -
Synthesis and Src Kinase Inhibitory Activity of 2-Phenyl- and 2-Thienyl-7-phe...
2-Phenyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles were recently reported to be inhibitors of Src kinase activity. In this study we present structure−activity... -
Additional file 9: of Liquid-phase hydrogenation of bio-refined succinic acid...
3__Ru-Co_EDS. (DOCX 277 kb) -
Additional file 1: Tables S1-S3. of Endocrine and exocrine pancreatic insuffi...
Comparision on the disease severity, complication and pancreatic necrosis between NGT, IGT and DM groups. The APACHE II score and Balthazar score in group DM was significant... -
Additional file 2: of Identification of three subtypes of triple-negative bre...
GES list, characteristics, bioinformatics, and references. (PDF 197 kb) -
r37980778c78--5af44bd04cb6838ff0c1016594e27249
Recently, we reported that 5,4‘-diamino-6,8,3‘-trifluoroflavone (1b) exhibits potent antitumor activity against certain types of human cancer cell lines both in vitro and in... -
Distinct binding and signaling activity of Acthar Gel compared to other melan...
To compare the binding and agonistic activity of Acthar® Gel and synthetic melanocortin receptor (MCR) agonists and examine how the activity of select agonists affects the in... -
Low-Band-Gap, σ-Conjugated Polymers: Poly(diarylstannanes)
Low-Band-Gap, σ-Conjugated Polymers: Poly(diarylstannanes)
