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A systematic review to investigate the measurement properties of goal attainm...
Abstract Background One of the main challenges for drug evaluation in rare diseases is the often heterogeneous course of these diseases. Traditional outcome measures may not be... -
The COMET Handbook: Version 1.0
Abstract The selection of appropriate outcomes is crucial when designing clinical trials in order to compare the effects of different interventions directly. For the findings to... -
Systematic review of clinical practice guidelines recommendations about prima...
Abstract Background Clinical care for older adults is complex and represents a growing problem. They are a diverse patient group with varying needs, frequent presence of...