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Risk perception of blood transfusions – a comparison of patients and allied h...
Background: Due to an increasing demand in health care services plans to substitute selective physician-conducted medical activities have become attractive. Because... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Role of goblet cell protein CLCA1 in murine DSS colitis
Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride... -
Deprescribing preventive cardiovascular medication in patients with predicted...
Abstract Background The use of cardiovascular medication for the primary prevention of cardiovascular disease (CVD) is potentially inappropriate when potential risks outweigh... -
Pharmacological pain relief and fear of childbirth in low risk women; seconda...
Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the... -
Pathological findings in spontaneously dead and euthanized sows – a descripti...
Abstract Background A high rate of euthanized and spontaneously dead sows causes production losses and likely indicates underlying... -
Marked deterioration in the quality of life of patients with idiopathic pulmo...
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic disease with a high symptom burden and poor survival that... -
User involvement and experiential knowledge in interprofessional rehabilitati...
Background: User involvement is increasingly important in developing relevant health care services. The aim of this study was to contribute to a deeper understanding of user... -
Subjective and objective assessment of physical activity in multiple sclerosi...
Abstract Background Physical activity (PA) is frequently restricted in people with multiple sclerosis (PwMS) and aiming to enhance PA is considered beneficial in this... -
Toll-like receptor-4 differentially mediates intestinal and extra-intestinal ...
Abstract Background Infections with multi-drug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa (PA) have become a serious threat particularly in... -
Omic personality: implications of stable transcript and methylation profiles ...
Abstract Background Personalized medicine is predicated on the notion that individual biochemical and genomic profiles are... -
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeru...
Abstract Background The rising incidence of multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa has become a serious issue in prevention of its... -
Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in i...
Background: The clinical utility of serum procalcitonin levels in guiding antibiotic treatment decisions in patients with sepsis remains unclear. This patient-level... -
A transcriptomic snapshot of early molecular communication between Pasteuria ...
© The Author(s). 2018 -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
Physiologically variable ventilation reduces regional lung inflammation in a ...
Abstract Background Benefits of variable mechanical ventilation based on the physiological breathing pattern have been observed both in healthy and injured lungs. These benefits... -
Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency pro...
Abstract Background Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist... -
The cost of influenza-associated hospitalizations and outpatient visits in Kenya
Background: We estimated the cost-per-episode and the annual economic burden associated with influenza in Kenya. Methods: From July 2013–August 2014, we recruited patients with... -
Factors influencing patient and health care delays in Oropharyngeal Cancer
Abstract Background The incidence of human papillomavirus (HPV)–associated oropharyngeal squamous cell carcinoma (OPSCC) is increasing. Patients with HPV-associated and... -
The role of the intra-abdominal view in complicated intra-abdominal infections
Abstract Background The prognostic role of what a surgeon observes in the abdomen of patients with complicated intra-abdominal...
