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Research capacity of Australian and New Zealand emergency medicine departments
Abstract Background Large, multicentre studies are required in emergency medicine to advance clinical care and improve patient outcomes. The Australasian College for Emergency... -
Acanthamoeba containing endosymbiotic chlamydia isolated from hospital enviro...
Abstract Background Environmental chlamydiae belonging to the Parachlamydiaceae are obligate intracellular bacteria that infect Acanthamoeba, a free-living amoeba, and are a... -
HIV epidemiology among female sex workers and their clients in the Middle Eas...
Abstract Background HIV epidemiology among female sex workers (FSWs) and their clients in the Middle East and North Africa (MENA) region is poorly understood. We addressed this... -
New dominant spa type t2741 in livestock-associated MRSA (CC398-MRSA-V) in Fi...
Abstract Background The emergence of livestock-associated MRSA has become a growing public health concern worldwide. Studies elucidating the population structure, as well as... -
Purification and genetic characterization of gassericin E, a novel co-culture...
Abstract Background Lactobacillus gasseri is one of the dominant Lactobacillus species in the vaginal ecosystem. Some strains of this species have a high potential for being... -
Differential roles for pathogenicity islands SPI-13 and SPI-8 in the interact...
Abstract Background Salmonella pathogenicity island (SPI)-13 is conserved in many serovars of S. enterica, including S. Enteritidis, S. Typhimurium and S. Gallinarum. However,... -
Divergent transcriptomic responses underlying the ranaviruses-amphibian inter...
Abstract Background Ranaviruses (family Iridoviridae, nucleocytoplasmic large DNA viruses) have been reported as promiscuous pathogens of cold-blooded vertebrates. Rana grylio... -
Flying ticks: anciently evolved associations that constitute a risk of infect...
Abstract Ticks are important vectors of emerging zoonotic diseases affecting human and animal health worldwide. Ticks are often found on wild birds, which have been long... -
HIV-1 molecular transmission clusters in nine European countries and Canada: ...
Abstract Background Knowledge of HIV-1 molecular transmission clusters (MTCs) is important, especially in large-scale datasets, for designing prevention programmes and public... -
The Dictyostelium discoideum homologue of Twinkle, Twm1, is a mitochondrial D...
Abstract Background DNA replication requires contributions from various proteins, such as DNA helicases; in mitochondria Twinkle is important for maintaining and replicating... -
Immune signatures for HIV-1 and HIV-2 induced CD4+T cell dysregulation in an ...
Abstract Background HIV-2 infection is characterised by a longer asymptomatic phase and slower AIDS progression than HIV-1 infection. Identifying unique immune signatures... -
Replication competence of virions induced from CD4+ lymphocytes latently infe...
Abstract Latently infected CD4 lymphocytes preclude cure of HIV infection, even with the most effective antiretroviral therapy. The replication competent latent HIV reservoir... -
Human-like NSG mouse glycoproteins sialylation pattern changes the phenotype ...
Abstract Background The use of immunodeficient mice transplanted with human hematopoietic stem cells is an accepted approach to study human-specific infectious diseases such as... -
Horizontal gene transfer is not a hallmark of the human genome
Abstract Crisp et al. recently reported that 145 human genes have been horizontally transferred from distant species. Here, I re-analyze those genes listed by Crisp et al. as... -
Production of human pro-relaxin H2 in the yeast Pichia pastoris
Abstract Background Initially known as the reproductive hormone, relaxin was shown to possess other therapeutically useful properties that include extracellular matrix... -
Prophages and adaptation of Staphylococcus aureus ST398 to the human clinic
Abstract Background It has been suggested that prophages in the ST398 S. aureus clone are responsible for expanding ST398's spectrum of action and increasing its ability to... -
Epithelial CD80 promotes immune surveillance of colonic preneoplastic lesions...
Abstract Background One of the most potent costimulatory molecules involved in the recognition and killing of tumor cells is CD80. However, its role and the molecular mechanisms... -
Characterisation of a niche-specific excretory–secretory peroxiredoxin from t...
Abstract Background The primary cause of parasitic gastroenteritis in small ruminants in temperate regions is the brown stomach worm, Teladorsagia circumcincta. Host immunity to... -
Medication transcription errors in hospitalized patient settings: a consensua...
Abstract Background Medication transcription errors (MTEs) are frequent in hospitalized patient settings. Definitions and scenarios that represent potential MTEs in the... -
Rare sex or out of reach equilibrium? The dynamics of F ...
Abstract Background Partially clonal organisms are very common in nature, yet the influence of partial asexuality on the temporal dynamics of genetic diversity remains poorly...
