-
Genome-wide DNA methylation at birth in relation to in utero arsenic exposure...
Abstract Background In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life.... -
Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...
Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood... -
Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...
Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to... -
Additional file 7: of The prominent alteration in transcriptome and metabolom...
Table S7. The homologous genes between M. bovis BCG and M. tuberculosis H37Rv. (XLS 1840 kb) -
The whole - genome expression analysis of peripheral blood mononuclear cells ...
Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the... -
Transcriptomic data from two primary cell models stimulating human monocytes ...
Abstract Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used... -
Andrographis paniculata transcriptome provides molecular insights into tissue...
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders.... -
SOX2 interferes with the function of CDX2 in bile acid-induced gastric intest...
Abstract Background Intestinal metaplasia (IM) is a premalignant lesion associated with gastric cancer. Both animal and clinical studies have revealed that bile acid reflux and... -
Systematic design of separation process for bioethanol production from corn s...
Abstract Separation process is very crucial in bioethanol production as it consumes the highest energy in the process. Unlike other works, this research systematically designed... -
Highly active promoters and native secretion signals for protein production d...
Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch... -
Pathway activity profiling of growth factor receptor network and stemness pat...
Abstract Background Gene expression profiling of rare cancers has proven challenging due to limited access to patient materials and requirement of intact, non-degraded RNA for... -
WhatsGNU: a tool for identifying proteomic novelty
Abstract To understand diversity in enormous collections of genome sequences, we need computationally scalable tools that can quickly contextualize individual genomes based on... -
Effects of intestinal colonization by Clostridium difficile and Staphylococcu...
Abstract Background Intestinal colonization by pathogenic bacteria is a risk factor for infection, and contributes to environmental contamination and disease dissemination.... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
Major differential gene regulation in Coxiella burnetii between in vivo and i...
Abstract Background Coxiella burnetii is the causative agent of the zoonotic disease Q fever. As it is an intracellular pathogen, infection by C. burnetii requires adaptation to... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Programme Reporting Standards (PRS) for improving the reporting of sexual, re...
Abstract Background Information about design, implementation, monitoring and evaluation is central to understand the impact of programmes within the field of sexual,... -
Reference genome and comparative genome analysis for the WHO reference strain...
The BCG live attenuated TB vaccine is one of the oldest and most widely used vaccines in human medicine. Each year, BCG vaccines are administered to over 100 million newborns... -
A metagenome-wide association study of gut microbiota in asthma in UK adults
Abstract Background Asthma, one of the most common chronic respiratory disorders, is associated with the hyper-activation of the T-cell subset of adaptive immunity. The gut... -
Subfunctionalization of peroxisome proliferator response elements accounts fo...
Abstract Background In the duplication-degeneration-complementation (DDC) model, a duplicated gene has three possible fates: it may lose functionality through the accumulation...
